(S)-(−)-α,α-Diphenyl-2-pyrrolidinemethanol tert-butyldimethylsilyl ether
(S)-(−)-α,α-Diphenyl-2-pyrrolidinemethanol tert-butyldimethylsilyl ether (CAS 864466-71-7) is a chiral organocatalyst with the molecular formula C23H33NOSi and a molecular weight of 367.60 g/mol. This compound is primarily utilised in asymmetric synthesis and as a building block in complex chemical synthesis. Its enantiomeric purity makes it valuable for stereoselective reactions in research and development settings.
- IUPAC
- (S)-(−)-α,α-Diphenylprolinol tert-butyldimethylsilyl ether,(S)-2-[(tert-Butyldimethylsiloxy)diphenylmethyl]pyrrolidine
- Synonyms
- (S)-2-[(tert-Butyldimethylsiloxy)diphenylmethyl]pyrrolidine(S)-(−)-α,α-Diphenylprolinol tert-butyldimethylsilyl ether
Asymmetric Synthesis
This chiral pyrrolidine derivative serves as a key reagent or catalyst in asymmetric synthesis. It enables the stereoselective formation of chiral molecules, which is crucial in the development of pharmaceuticals and fine chemicals.
Chiral Ligand Development
The compound can be employed in the synthesis of novel chiral ligands for transition metal catalysis. These ligands are vital for achieving high enantioselectivity in various catalytic transformations.
Organic Synthesis
As a versatile building block, it finds application in complex organic synthesis pathways. Its specific stereochemistry and functional groups allow for precise molecular construction.
| Molecular weight | 367.60 |
|---|---|
| Empirical formula | C23H33NOSi |
| Assay | ≥97% (HPLC) |
| Optical purity | enantiomeric excess: ≥98.0% |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-α,α-Diphenyl-2-pyrrolidinemethanol tert-butyldimethylsilyl ether used for?
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This compound is primarily used in asymmetric synthesis and as a chiral building block in organic synthesis. It is also utilised in the development of chiral ligands for catalysis.
What is the CAS number and chemical formula for this product?
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The CAS number is 864466-71-7 and the empirical formula is C23H33NOSi.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥97% (HPLC) and an enantiomeric excess of ≥98.0%. TSS does not represent this product as USP, BP, or EP grade.
How should (S)-(−)-α,α-Diphenyl-2-pyrrolidinemethanol tert-butyldimethylsilyl ether be handled?
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This compound is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area. Avoid breathing dust/fume/gas/mist/vapours/spray. If in eyes, rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Is this chemical available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including this product.
How can I request a sample or quote for this chemical?
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Please contact our sales team via the website or direct email to request a sample or a formal quotation.
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