Tripropyl orthoformate
Tripropyl orthoformate (CAS: 621-76-1), with the molecular formula CH(OCH2CH2CH3)3 and a molecular weight of 190.28, is a chemical compound belonging to the ortho ester family. It serves as a versatile building block and reagent in organic synthesis. Its applications span various chemical transformations, contributing to the development of diverse organic molecules within research and industrial settings.

Organic Synthesis Intermediate
Tripropyl orthoformate acts as a valuable intermediate in the synthesis of various organic compounds. Its reactivity allows for the introduction of specific functional groups or structural motifs in complex molecules.
Building Block in Chemical Research
As an organic building block, this compound is utilised in academic and industrial research laboratories for the exploration of new synthetic routes and the creation of novel chemical entities.
Reagent in Acetalisation and Formylation
Orthoesters like tripropyl orthoformate are commonly employed as formylating agents or in acetalisation reactions, facilitating the protection or modification of carbonyl compounds.
| Molecular weight | 190.28 |
|---|---|
| Linear formula | CH(OCH2CH2CH3)3 |
| Assay | 97% |
| Boiling point | 106-108 °C/40 mmHg(lit.) |
| Density | 0.883 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.407(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 72 °C / 161.6 °F |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tripropyl orthoformate used for?
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Tripropyl orthoformate is used as an intermediate and building block in organic synthesis, particularly in formylation and acetalisation reactions for chemical research and development.
What is the CAS number and chemical formula for Tripropyl orthoformate?
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The CAS number for Tripropyl orthoformate is 621-76-1, and its chemical formula is CH(OCH2CH2CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tripropyl orthoformate with an assay of 97%. This is a technical grade and is not represented as USP, BP, or EP.
How should Tripropyl orthoformate be handled safely?
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Tripropyl orthoformate is a warning hazard compound that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Always use appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, and handle in a well-ventilated area.
Does TSS export Tripropyl orthoformate?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Tripropyl orthoformate.
How can I request a sample or quote for Tripropyl orthoformate?
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To request a sample or quote for Tripropyl orthoformate, please contact our sales team through the website or by phone.
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