Methyl (2S)-glycidate
Methyl (2S)-glycidate (CAS: 118712-39-3), with the molecular formula C4H6O3 and a molecular weight of 102.09 g/mol, is a chiral epoxide crucial for asymmetric synthesis. This versatile building block is employed in the development of complex organic molecules and pharmaceutical intermediates. Its specific stereochemistry makes it invaluable in stereoselective reactions, contributing to the efficient construction of chiral targets in organic chemistry research and development.
- IUPAC
- Methyl (S)-oxiranecarboxylate
Chiral Building Block in Organic Synthesis
Methyl (2S)-glycidate serves as a fundamental chiral synthon for constructing enantiomerically pure compounds. Its epoxide ring is readily opened by various nucleophiles, introducing chirality into the target molecule with high stereochemical control.
Intermediate for Pharmaceutical Development
This compound is utilised in the synthesis of active pharmaceutical ingredients (APIs) and their intermediates where precise stereochemistry is critical for biological activity. Its structure allows for facile functionalisation to create diverse drug candidates.
Asymmetric Synthesis Research
Researchers employ Methyl (2S)-glycidate in academic and industrial settings to explore novel stereoselective transformations and develop new synthetic methodologies. It is a valuable tool for creating complex chiral architectures.
| Molecular weight | 102.09 |
|---|---|
| Empirical formula | C4H6O3 |
| Assay | 98% |
| Density | 1.166 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.42(lit.) |
| Optical activity | [α]20/D −32°, c = 1 in chloroform |
| Optical purity | ee: 99% (GLC) |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 72 °C / 161.6 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl (2S)-glycidate used for?
+
Methyl (2S)-glycidate is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the development of pharmaceuticals and other complex organic molecules where specific stereochemistry is required.
What are the CAS number and formula for Methyl (2S)-glycidate?
+
The CAS number for Methyl (2S)-glycidate is 118712-39-3, and its empirical formula is C4H6O3.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Methyl (2S)-glycidate with an assay of 98%. This product is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should Methyl (2S)-glycidate be handled and stored safely?
+
Methyl (2S)-glycidate is a Warning substance (GHS07) and is classified with hazard statements H315, H319, and H335, indicating it may cause skin irritation, serious eye irritation, and respiratory irritation. Handle with appropriate personal protective equipment, including eyeshields and gloves, in a well-ventilated area. Store at 2-8°C as indicated.
How is Methyl (2S)-glycidate packed, shipped, and exported?
+
Methyl (2S)-glycidate is carefully packed according to international shipping regulations for chemical substances and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for Methyl (2S)-glycidate?
+
To request a sample or a quotation for Methyl (2S)-glycidate, please contact the Tech Serve Solutions sales team through our website or direct contact details, providing your specific requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis