Methyl (2S)-(−)-2-(hydroxydiphenylmethyl)-1-pyrrolidinecarboxylate
Methyl (2S)-(−)-2-(hydroxydiphenylmethyl)-1-pyrrolidinecarboxylate (CAS: 352535-68-3) is a chiral organic compound with the molecular formula C19H21NO3 and a molecular weight of 311.37 g/mol. This compound serves as a valuable building block in asymmetric synthesis, primarily utilised for the construction of complex chiral molecules. Its specific stereochemistry makes it important in stereoselective reactions within chemical synthesis and pharmaceutical research.
- IUPAC
- (S)-(−)-N-Carbomethoxy-α,α-diphenyl-2-pyrrolidinemethanol

Asymmetric Synthesis
This compound is a key chiral building block utilised in asymmetric synthesis. It enables the stereoselective construction of complex organic molecules, crucial for pharmaceutical development and fine chemical manufacturing.
Chiral Ligand Precursor
The pyrrolidine scaffold with diphenylmethanol substitution makes it a potential precursor for chiral ligands used in transition metal catalysis. Such ligands are vital for enantioselective transformations.
Pharmaceutical Intermediate
Its defined stereochemistry and functional groups make it suitable as an intermediate in the synthesis of pharmacologically active compounds. It aids in building specific stereoisomers of drug candidates.
Research and Development
Used in academic and industrial research laboratories for exploring novel synthetic routes and developing new chiral methodologies. Its availability supports innovation in stereoselective organic chemistry.
| Molecular weight | 311.37 |
|---|---|
| Empirical formula | C19H21NO3 |
| Assay | 98% |
| Optical activity | [α]20/D −137°, c = 1 in chloroform |
| Melting point | 160-164 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl (2S)-(−)-2-(hydroxydiphenylmethyl)-1-pyrrolidinecarboxylate used for?
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This compound is primarily used as a chiral building block in asymmetric synthesis, as a precursor for chiral ligands, and as an intermediate in pharmaceutical research and development.
What are the CAS number and formula for this chemical?
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The CAS number is 352535-68-3 and the empirical formula is C19H21NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 98%. We do not represent this product as USP, BP, or EP grade unless explicitly stated in the product specifications.
What are the safety and handling precautions for this compound?
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This compound requires the use of Eyeshields and Gloves. A respirator filter of type N95 (US) or P1 (EN143) is recommended. It is classified under WGK 2 in Germany.
How is this product shipped and exported?
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As a global supplier and exporter of fine chemicals, TSS ensures appropriate packaging and documentation for domestic and international shipments, adhering to all relevant regulations.
How can I request a sample or a quote?
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Please contact our sales team or use the online form on our website to request a sample or a detailed quotation for Methyl (2S)-(−)-2-(hydroxydiphenylmethyl)-1-pyrrolidinecarboxylate.
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