Methyl (1-methylindolyl)-3-glyoxylate
Methyl (1-methylindolyl)-3-glyoxylate (CAS: 151490-40-3) is a chemical compound with the molecular formula C12H11NO3 and a molecular weight of 217.22. Supplied by Tech Serve Solutions with an assay of 97%, this indole derivative serves as a valuable building block in chemical synthesis. Its applications primarily lie in the preparation of complex organic molecules, including pharmaceutical intermediates and research compounds.

Synthesis of Sotrastaurin Analogues
This compound is utilised as a reactant in the synthetic routes towards sotrastaurin analogues, which are investigated for various biological activities. The indole moiety provides a key structural element for these complex molecules.
Preparation of Protein Kinase C Inhibitors
Methyl (1-methylindolyl)-3-glyoxylate is employed in the preparation of protein kinase C (PKC) inhibitors. These compounds are of interest in pharmacological research due to the role of PKC in cellular signalling pathways.
Synthesis of Indolyl Diols
It serves as a reactant in the preparation of indolyl diols. This application highlights its utility in generating diverse heterocyclic structures for further chemical exploration and development.
| Molecular weight | 217.22 |
|---|---|
| Empirical formula | C12H11NO3 |
| Assay | 97% |
| Application | • Reactant for synthesis of sotrastaurin analogs1• Reactant for preparation of protein kinase C (PKC) inhibitors2• Reactant for preparation of indolyl diols3 |
| Melting point | 96-100 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl (1-methylindolyl)-3-glyoxylate used for?
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Methyl (1-methylindolyl)-3-glyoxylate is primarily used as a reactant in chemical synthesis for preparing sotrastaurin analogues, protein kinase C (PKC) inhibitors, and indolyl diols.
What are the CAS number and molecular formula for Methyl (1-methylindolyl)-3-glyoxylate?
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The CAS number is 151490-40-3, and the molecular formula is C12H11NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl (1-methylindolyl)-3-glyoxylate with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Methyl (1-methylindolyl)-3-glyoxylate be handled safely?
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This compound is a Warning substance and may cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, in a well-ventilated area. Avoid breathing dust.
How is Methyl (1-methylindolyl)-3-glyoxylate packed, shipped, and exported?
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Tech Serve Solutions handles the packing, shipping, and export of chemicals with stringent adherence to international regulations, ensuring safe and compliant delivery worldwide. Specific packaging details are available upon request.
How can I request a sample or quote for Methyl (1-methylindolyl)-3-glyoxylate?
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To request a sample or quote, please contact our sales team through the website or by direct inquiry, providing your specific requirements and delivery details.
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