Methoxypolyethylene glycol azide
Methoxypolyethylene glycol azide (CAS: 89485-61-0) is a monofunctional polyethylene glycol derivative featuring an azide terminus. With an average molecular weight of 5,000, it serves as a versatile building block in chemical synthesis and materials science. Its primary applications lie in bioconjugation, surface modification, and the development of advanced polymers, leveraging the reactivity of the azide group for click chemistry reactions.
- IUPAC
- α-Methoxy-ω-azido-PEG,O-(2-Azidoethyl)-O′-methylpolyethylene glycol,PEG-Azide,mPEG Azide
- Synonyms
- α-Methoxy-ω-azido-PEGO-(2-Azidoethyl)-O′-methylpolyethylene glycolPEG-AzidemPEG Azide
Bioconjugation Chemistry
Methoxypolyethylene glycol azide is extensively used to functionalise biomolecules such as peptides, proteins, and nucleic acids. The azide group readily participates in copper-catalysed azide-alkyne cycloaddition (CuAAC) or strain-promoted azide-alkyne cycloaddition (SPAAC) reactions, enabling the attachment of PEG chains for improved solubility, stability, and reduced immunogenicity.
Surface Modification
This reagent facilitates the modification of surfaces and nanoparticles. By immobilising methoxypolyethylene glycol azide onto a substrate, its azide functionality can then be used to attach other molecules, creating biocompatible coatings, drug delivery systems, or biosensing platforms.
Polymer Synthesis and Materials Science
It acts as a valuable monomer or functionalisation agent in polymer synthesis. The PEG chain imparts desirable properties like flexibility and hydrophilicity, while the azide group allows for post-polymerisation modification and cross-linking, contributing to the development of novel materials.
| Density | 1.105 g/mL at 25 °C |
|---|---|
| Refractive index | n20/D 1.458 |
| Storage temperature | 2-8°C |
| Melting point | 55-60 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Description | 5000 |
|---|---|
| Mol Wt | PEG average Mn 5,000 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methoxypolyethylene glycol azide used for?
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Methoxypolyethylene glycol azide (CAS: 89485-61-0) is primarily used in bioconjugation for functionalising biomolecules, modifying surfaces and nanoparticles, and in polymer synthesis and materials science, often employing click chemistry reactions.
What is the CAS number and formula for Methoxypolyethylene glycol azide?
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The CAS number for Methoxypolyethylene glycol azide is 89485-61-0. The molecular formula is not provided in the data.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methoxypolyethylene glycol azide with an average Mn of 5,000. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Methoxypolyethylene glycol azide be handled and stored?
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Handle Methoxypolyethylene glycol azide with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at 2-8°C.
Is Methoxypolyethylene glycol azide a controlled substance?
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The provided data does not indicate that Methoxypolyethylene glycol azide is a controlled substance.
How are Tech Serve Solutions' products packed, shipped, and exported?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals, ensuring appropriate packaging and adherence to international shipping regulations for hazardous materials.
How can I request a sample or quote for Methoxypolyethylene glycol azide?
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To request a sample or quote for Methoxypolyethylene glycol azide, please contact the Tech Serve Solutions sales team through our website or by phone.
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