(S)-(−)-α-Amino-γ-butyrolactone hydrobromide

CAS 15295-77-9C4H7NO2 · HBrChemical Synthesis

(S)-(−)-α-Amino-γ-butyrolactone hydrobromide (CAS: 15295-77-9), with the molecular formula C4H7NO2 · HBr and a molecular weight of 182.02 g/mol, is a chiral building block supplied by Tech Serve Solutions. This compound is primarily utilised in organic synthesis, particularly for preparing pseudopeptide inhibitors for Ras farnesyl-protein transferase and selenomethionine. It is offered with a high purity of 99%.

IUPAC: L-Homoserine lactone hydrobromide

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(S)-(−)-α-Amino-γ-butyrolactone hydrobromide (C4H7NO2 · HBr) — chemical structure, CAS 15295-77-9; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral Building BlocksLactonesOrganic Building Blocks

01 /Applications

Preparation of Pseudopeptide Inhibitors

Utilised in the synthesis of pseudopeptide inhibitors targeting Ras farnesyl-protein transferase, a key enzyme in cellular signalling pathways. Its chiral nature is crucial for the specificity of these inhibitors.

Synthesis of Selenomethionine

Serves as a precursor in the preparation of selenomethionine, an analogue of the amino acid methionine containing selenium. This is important in biochemical research and protein studies.

Chiral Building Block in Organic Synthesis

As a chiral lactone derivative, it is a valuable synthon for introducing specific stereochemistry into complex organic molecules. Its applications span various areas of synthetic organic chemistry.

02 /Properties

Molecular weight	182.02
Empirical formula	C4H7NO2 · HBr
Assay	99%
Optical activity	[α]20/D −21°, c = 1 in H2O
Storage temperature	2-8°C
Application	Used to prepare pseudopeptide inhibitors for Ras farnesyl-protein transferase1 as well as selenomethionine.2
Melting point	225 °C (dec.)(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

15295-77-9

MDL number

MFCD00674493

PubChem substance

24870732

Beilstein registry

3912375

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-(−)-α-Amino-γ-butyrolactone hydrobromide used for?

(S)-(−)-α-Amino-γ-butyrolactone hydrobromide is used in organic synthesis, primarily for preparing pseudopeptide inhibitors for Ras farnesyl-protein transferase and for the synthesis of selenomethionine.

What is the CAS number and molecular formula?

The CAS number is 15295-77-9 and the molecular formula is C4H7NO2 · HBr.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (S)-(−)-α-Amino-γ-butyrolactone hydrobromide with an assay of 99%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

What are the safety and handling recommendations?

Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound has a WGK rating of 3.

How is the product stored and shipped?

It should be stored at 2-8°C. Tech Serve Solutions exports fine chemicals globally, adhering to all necessary regulations for safe and compliant transportation.