(4R,5S)-4-Methyl-5-phenyl-3-propionyl-2-oxazolidinone
(4R,5S)-4-Methyl-5-phenyl-3-propionyl-2-oxazolidinone (CAS 77877-20-4) is a chiral auxiliary with the molecular formula C13H15NO3 and a molecular weight of 233.26 g/mol. This oxazolidinone derivative is valuable in organic synthesis for controlling stereochemistry. It is typically supplied with an assay of ≥97.0% and is used in asymmetric synthesis and chemical research to achieve enantioselective transformations.
- Synonyms
- C13H15NO3(4R,5S)-4-Methyl-5-phenyl-3-propionyl-2-oxazolidinone

Asymmetric Synthesis
Utilised as a chiral auxiliary to direct the stereochemical outcome of reactions, enabling the synthesis of enantiomerically enriched compounds.
Chiral Building Block
Serves as a key intermediate in the construction of complex chiral molecules, particularly in pharmaceutical and fine chemical research.
Stereoselective Transformations
Facilitates reactions such as alkylations, aldol additions, and conjugate additions with high levels of stereocontrol.
| Molecular weight | 233.26 |
|---|---|
| Empirical formula | C13H15NO3 |
| Assay | ≥97.0% (sum of enantiomers, GC) |
| Density | 1.161 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.530 |
| Optical activity | [α]20/D +42±1°, c = 2% in methylene chloride |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Flash point | 109 °C / 228.2 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (4R,5S)-4-Methyl-5-phenyl-3-propionyl-2-oxazolidinone used for?
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This compound is primarily used as a chiral auxiliary in asymmetric synthesis to control the stereochemical outcome of chemical reactions.
What is the CAS number and formula for this oxazolidinone derivative?
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The CAS number is 77877-20-4, and the empirical formula is C13H15NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥97.0% (sum of enantiomers, GC). It is not supplied as USP, BP, or EP grade.
How should (4R,5S)-4-Methyl-5-phenyl-3-propionyl-2-oxazolidinone be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. Observe appropriate laboratory safety protocols and refer to the Safety Data Sheet for detailed guidance. The flash point is 109 °C (228.2 °F).
Is this chemical a controlled substance?
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The provided data does not indicate that this chemical is a controlled substance.
How is this product shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, handling packaging and shipping to meet international standards.
How can I request a sample or a quote?
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Please contact our sales team through the website or by phone to request a sample or a quotation for this product.
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