(S)-(−)-α-Hydroxy-γ-butyrolactone
(S)-(−)-α-Hydroxy-γ-butyrolactone (CAS: 52079-23-9, C4H6O3) is a chiral building block with a molecular weight of 102.09 g/mol. This optically active lactone is primarily utilised in asymmetric synthesis. Its applications include the preparation of complex molecules such as the polyether antibiotic monensin, functionalized side chains for vitamin D analogues, and various pesticides. Available at 97% purity, it serves as a key intermediate in advanced organic synthesis.
Monensin Synthesis
This compound is a crucial precursor in the synthesis of monensin, a polyether antibiotic. Its chiral nature is essential for constructing the complex molecular architecture of this important pharmaceutical agent.
Vitamin D Analogues
It is employed in the preparation of functionalised D-ring side chains for various vitamin D analogues. This allows for the creation of novel compounds with potentially modified biological activities.
Pesticide Intermediates
The compound serves as an intermediate in the synthesis of certain pesticides. Its specific chemical structure and chirality are leveraged to develop targeted agrochemical solutions.
| Molecular weight | 102.09 |
|---|---|
| Empirical formula | C4H6O3 |
| Assay | 97% |
| Boiling point | 133 °C/10 mmHg(lit.) |
| Density | 1.309 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.467(lit.) |
| Optical activity | [α]23/D −68°, c = 1.15 in chloroform |
| Optical purity | ee: 96% (GLC) |
| Storage temperature | 2-8°C |
| Application | Used to prepare the polyether antibiotic monensin,1 functionalized D-ring side chains of vitamin D analogs,2 and pesticides.3 |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Flash point | >113 °C / >235.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-α-Hydroxy-γ-butyrolactone used for?
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(S)-(−)-α-Hydroxy-γ-butyrolactone is used in asymmetric synthesis, including the preparation of the polyether antibiotic monensin, functionalized D-ring side chains of vitamin D analogs, and pesticides.
What are the CAS number and molecular formula?
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The CAS number for (S)-(−)-α-Hydroxy-γ-butyrolactone is 52079-23-9, and its molecular formula is C4H6O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-α-Hydroxy-γ-butyrolactone with an assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should (S)-(−)-α-Hydroxy-γ-butyrolactone be handled and stored?
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Handling requires Eyeshields and Gloves. Store at 2-8°C. The flash point is >113 °C (>235.4 °F), and it has a WGK rating of 3 in Germany, indicating a high hazard to water.
Is (S)-(−)-α-Hydroxy-γ-butyrolactone a controlled substance?
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The provided data does not indicate that (S)-(−)-α-Hydroxy-γ-butyrolactone is a controlled substance.
How is this chemical supplied and exported by TSS?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals. For specific packaging and export details for (S)-(−)-α-Hydroxy-γ-butyrolactone, please contact our sales team.
How can I request a sample or quote for (S)-(−)-α-Hydroxy-γ-butyrolactone?
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To request a sample or obtain a quote for (S)-(−)-α-Hydroxy-γ-butyrolactone, please utilise the 'Request Quote' or 'Request Sample' buttons on our website or contact our customer service department directly.
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