Boc-D-Nle-OH
Boc-D-Nle-OH (CAS 55674-63-0), with the molecular formula C11H21NO4, is a key derivative of the unnatural amino acid D-norleucine. This compound is widely employed in chemical biology and synthesis, particularly within peptide chemistry. Its protected structure makes it an invaluable building block for creating complex peptides and peptidomimetics, contributing to advancements in medicinal chemistry and drug discovery.
- IUPAC
- Boc-D-norleucine
- Synonyms
- Boc-D-norleucine
Peptide Synthesis
Boc-D-Nle-OH serves as a protected building block in solid-phase and solution-phase peptide synthesis. The tert-butyloxycarbonyl (Boc) group offers reliable protection of the amine functionality, facilitating controlled coupling reactions.
Medicinal Chemistry
This unnatural amino acid derivative is utilised in the design and synthesis of novel therapeutic agents. Incorporating D-norleucine into peptide backbones can enhance stability against enzymatic degradation and modulate biological activity.
Chemical Biology Research
Boc-D-Nle-OH is employed in chemical biology for creating labelled peptides or peptidomimetics for studying biological processes. Its unique structural properties allow for probing protein-protein interactions or developing enzyme inhibitors.
Organic Synthesis
As a versatile chiral intermediate, Boc-D-Nle-OH finds application in complex organic synthesis beyond peptide chemistry. It can be a starting material for creating various chiral molecules and functionalised derivatives.
| Molecular weight | 231.29 |
|---|---|
| Empirical formula | C11H21NO4 |
| Assay | ≥98.0% |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-D-Nle-OH used for?
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Boc-D-Nle-OH is primarily used as a protected building block in peptide synthesis, medicinal chemistry research, and chemical biology for constructing unnatural peptides and peptidomimetics.
What is the CAS number and molecular formula for Boc-D-Nle-OH?
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The CAS number for Boc-D-Nle-OH is 55674-63-0, and its molecular formula is C11H21NO4.
What grade and purity does Tech Serve Solutions supply for Boc-D-Nle-OH?
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Tech Serve Solutions supplies Boc-D-Nle-OH with an assay of ≥98.0%. This product is intended for research and laboratory use; TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling precautions for Boc-D-Nle-OH?
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When handling Boc-D-Nle-OH, it is essential to use safety measures including eyeshields and gloves. The compound is classified under WGK Germany 3, indicating a hazard to water. Store in a cool, dry place away from incompatible materials.
How is Boc-D-Nle-OH packed and shipped?
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Boc-D-Nle-OH is carefully packed to ensure integrity during transit and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations for chemical compounds.
How can I request a sample or quote for Boc-D-Nle-OH?
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To request a sample or a quotation for Boc-D-Nle-OH, please contact our sales department through the website or by calling our customer service line.
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