Boc-D-Lys-OH
Nα-(tert-Butoxycarbonyl)-D-lysine (CAS: 106719-44-2, Formula: C11H22N2O4) is a protected amino acid derivative, specifically the D-enantiomer of lysine with a Boc protecting group on the alpha-amino function. It is widely employed in peptide synthesis and chemical biology research. This compound serves as a crucial building block for constructing peptides with specific sequences and functionalities, contributing to advancements in drug discovery and biochemical studies.
- IUPAC
- Nα-(tert-Butoxycarbonyl)-D-lysine,Nα-Boc-D-lysine
- Synonyms
- Nα-Boc-D-lysineNalpha-(tert-Butoxycarbonyl)-D-lysine

Peptide Synthesis
Nα-Boc-D-lysine is a key intermediate in solid-phase and solution-phase peptide synthesis. The Boc group protects the alpha-amino group, allowing for controlled coupling reactions at the carboxyl terminus. Its D-chirality enables the incorporation of non-natural amino acid residues into peptide chains.
Chemical Biology Research
This compound is used in studies involving modified peptides or peptidomimetics. It allows researchers to investigate the impact of D-amino acids and lysine side-chain modifications on biological activity, protein structure, and enzyme interactions.
Drug Discovery and Development
As a versatile building block, Nα-Boc-D-lysine facilitates the synthesis of novel therapeutic peptides. Its incorporation can influence peptide stability, receptor binding affinity, and pharmacokinetic properties, aiding in the development of new drug candidates.
| Molecular weight | 246.30 |
|---|---|
| Empirical formula | C11H22N2O4 |
| Assay | 98% |
| Optical activity | [α]22/D -24°, c = 0.5% in methanol |
| Storage temperature | 2-8°C |
| Melting point | 205-210 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nα-(tert-Butoxycarbonyl)-D-lysine used for?
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Nα-(tert-Butoxycarbonyl)-D-lysine is primarily used as a protected amino acid building block in peptide synthesis and chemical biology research for creating peptides with specific sequences and functionalities.
What are the CAS number and formula for Nα-(tert-Butoxycarbonyl)-D-lysine?
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The CAS number is 106719-44-2, and the empirical formula is C11H22N2O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nα-(tert-Butoxycarbonyl)-D-lysine with a minimum assay of 98%. This product is intended for research and development purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Nα-(tert-Butoxycarbonyl)-D-lysine be handled and stored?
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According to the safety data, this compound may cause skin irritation and serious eye irritation. It is classified under WGK Germany 3. It should be stored at refrigerated temperatures between 2-8°C.
Is Nα-(tert-Butoxycarbonyl)-D-lysine a controlled substance?
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The provided data does not indicate that Nα-(tert-Butoxycarbonyl)-D-lysine is a controlled substance.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions carefully packs and exports fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, adhering to all relevant shipping regulations and quality standards.
How can I request a sample or quote for Nα-(tert-Butoxycarbonyl)-D-lysine?
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Please contact our sales team through the website or by phone to request a sample or obtain a quotation for Nα-(tert-Butoxycarbonyl)-D-lysine.
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