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Boc-D-Phe(3-CF3)-OH

CAS 82317-82-6C15H18F3NO4Chemical Synthesis

Boc-D-Phe(3-CF3)-OH (CAS: 82317-82-6), with the molecular formula C15H18F3NO4 and a molecular weight of 333.30, is a trifluoromethylated unnatural amino acid derivative. This protected amino acid is primarily utilised in chemical synthesis, particularly within peptide chemistry and chemical biology research. Its specific structure makes it a valuable building block for creating novel peptides and complex organic molecules, contributing to advancements in drug discovery and material science.

IUPAC
Boc-3-(trifluoromethyl)-D-phenylalanine
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Boc-D-Phe(3-CF3)-OH (C15H18F3NO4) — chemical structure, CAS 82317-82-6; Chemistry, fine chemical supplied by Tech Serve Solutions
Chemical BiologyChemical SynthesisPeptide ChemistryPhenylalanine Derivatives
01 /Applications

Peptide Synthesis

Serves as a chiral building block in solid-phase or solution-phase peptide synthesis for the incorporation of unnatural amino acid residues. The trifluoromethyl group and Boc protection offer unique properties and synthetic control.

Chemical Biology Research

Used in the design and synthesis of peptides and peptidomimetics with modified properties, such as enhanced stability, altered binding affinities, or specific conformational preferences for biological studies.

Organic Synthesis

A versatile intermediate in the synthesis of complex organic molecules and fluorinated compounds, where the trifluoromethylphenylalanine motif is desired.

02 /Properties
Molecular weight333.30
Empirical formulaC15H18F3NO4
Assay≥98.0% (TLC)
Optical activity[α]20/D −7.0±0.5°, c = 1% in methanol
Melting point135-138 °C
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
82317-82-6
MDL number
MFCD00672525
Beilstein registry
5133890
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Boc-D-Phe(3-CF3)-OH used for?

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Boc-D-Phe(3-CF3)-OH is used as a building block in peptide synthesis, chemical biology research, and organic synthesis, particularly for creating fluorinated peptides and complex molecules.

What are the CAS number and molecular formula for Boc-D-Phe(3-CF3)-OH?

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The CAS number is 82317-82-6, and the molecular formula is C15H18F3NO4.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Boc-D-Phe(3-CF3)-OH with an assay of ≥98.0% (TLC). This product is not represented as USP, BP, or EP grade.

How should Boc-D-Phe(3-CF3)-OH be handled?

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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter.

Is Boc-D-Phe(3-CF3)-OH shipped internationally?

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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Boc-D-Phe(3-CF3)-OH.

How can I request a sample or quote for Boc-D-Phe(3-CF3)-OH?

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Please contact our sales team through the website or by phone to request a sample or a formal quotation.

Need Boc-D-Phe(3-CF3)-OH in a specific grade or volume?