Boc-D-Phe(3-CF3)-OH
Boc-D-Phe(3-CF3)-OH (CAS: 82317-82-6), with the molecular formula C15H18F3NO4 and a molecular weight of 333.30, is a trifluoromethylated unnatural amino acid derivative. This protected amino acid is primarily utilised in chemical synthesis, particularly within peptide chemistry and chemical biology research. Its specific structure makes it a valuable building block for creating novel peptides and complex organic molecules, contributing to advancements in drug discovery and material science.
- IUPAC
- Boc-3-(trifluoromethyl)-D-phenylalanine

Peptide Synthesis
Serves as a chiral building block in solid-phase or solution-phase peptide synthesis for the incorporation of unnatural amino acid residues. The trifluoromethyl group and Boc protection offer unique properties and synthetic control.
Chemical Biology Research
Used in the design and synthesis of peptides and peptidomimetics with modified properties, such as enhanced stability, altered binding affinities, or specific conformational preferences for biological studies.
Organic Synthesis
A versatile intermediate in the synthesis of complex organic molecules and fluorinated compounds, where the trifluoromethylphenylalanine motif is desired.
| Molecular weight | 333.30 |
|---|---|
| Empirical formula | C15H18F3NO4 |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]20/D −7.0±0.5°, c = 1% in methanol |
| Melting point | 135-138 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-D-Phe(3-CF3)-OH used for?
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Boc-D-Phe(3-CF3)-OH is used as a building block in peptide synthesis, chemical biology research, and organic synthesis, particularly for creating fluorinated peptides and complex molecules.
What are the CAS number and molecular formula for Boc-D-Phe(3-CF3)-OH?
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The CAS number is 82317-82-6, and the molecular formula is C15H18F3NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-D-Phe(3-CF3)-OH with an assay of ≥98.0% (TLC). This product is not represented as USP, BP, or EP grade.
How should Boc-D-Phe(3-CF3)-OH be handled?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter.
Is Boc-D-Phe(3-CF3)-OH shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Boc-D-Phe(3-CF3)-OH.
How can I request a sample or quote for Boc-D-Phe(3-CF3)-OH?
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Please contact our sales team through the website or by phone to request a sample or a formal quotation.
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