Boc-D-Phe(3-Cl)-OH
Boc-D-Phe(3-Cl)-OH, identified by CAS number 80102-25-6, is a modified amino acid derivative with the empirical formula C14H18ClNO4 and a molecular weight of 299.75 g/mol. This compound serves as a valuable building block in chemical synthesis, particularly within peptide chemistry and the development of unnatural amino acid derivatives. Its specific structure makes it a useful reagent in chemical biology research and for creating novel peptide sequences with unique properties.
- IUPAC
- Boc-3-chloro-D-phenylalanine
- Synonyms
- Boc-3-chloro-D-phenylalanine

Peptide Synthesis
Utilised as a protected unnatural amino acid in solid-phase or solution-phase peptide synthesis to introduce specific structural modifications. It enables the creation of peptides with enhanced stability or altered biological activity.
Chemical Biology Research
Employed as a tool compound for investigating protein structure-function relationships and for developing peptidomimetics. Its chlorinated phenyl ring offers a unique probe for biological interactions.
Drug Discovery
Serves as an intermediate in the synthesis of novel pharmaceutical candidates and complex organic molecules. The Boc protection and the chlorinated phenylalanine moiety can be critical for scaffold development.
Synthesis of Unnatural Amino Acids
Acts as a precursor or intermediate in the broader field of unnatural amino acid derivative synthesis, expanding the toolkit for medicinal chemists and researchers.
| Molecular weight | 299.75 |
|---|---|
| Empirical formula | C14H18ClNO4 |
| Assay | ≥98.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-D-Phe(3-Cl)-OH used for?
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Boc-D-Phe(3-Cl)-OH is primarily used in peptide synthesis, chemical biology research, and drug discovery as a protected unnatural amino acid derivative.
What is the CAS number and empirical formula for Boc-D-Phe(3-Cl)-OH?
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The CAS number is 80102-25-6 and the empirical formula is C14H18ClNO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-D-Phe(3-Cl)-OH with a purity of ≥98.0% (HPLC). We do not represent this product as USP, BP, or EP grade.
What are the safety and handling requirements for Boc-D-Phe(3-Cl)-OH?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound has a WGK Germany rating of 3, indicating a significant hazard to water.
How is Boc-D-Phe(3-Cl)-OH packed, shipped, and exported?
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Products are carefully packed to ensure integrity during transit and are expertly handled for global export by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a sample or quote for Boc-D-Phe(3-Cl)-OH?
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Please contact our sales team via the website or by phone to request a sample or a detailed quotation for Boc-D-Phe(3-Cl)-OH.
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