Boc-D-Phe(3-F)-OH

CAS 114873-11-9C14H18FNO4Chemical Synthesis

Boc-D-Phe(3-F)-OH (CAS: 114873-11-9), a fluorinated unnatural amino acid derivative, has the molecular formula C14H18FNO4 and a molecular weight of 283.30 g/mol. This compound serves as a valuable building block in chemical synthesis, particularly within peptide chemistry and chemical biology research. Its unique structure allows for the incorporation of fluorinated phenylalanine analogues into peptides, enabling studies of protein structure, function, and drug development.

IUPAC: Boc-3-fluoro-D-phenylalanine

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Boc-D-Phe(3-F)-OH (C14H18FNO4) — chemical structure, CAS 114873-11-9; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical BiologyChemical SynthesisPeptide ChemistryPhenylalanine Derivatives

01 /Applications

Peptide Synthesis

Utilised as a protected unnatural amino acid in solid-phase or solution-phase peptide synthesis to introduce a 3-fluoro-D-phenylalanine residue. This modification can influence peptide conformation, receptor binding, and metabolic stability.

Chemical Biology Research

Incorporated into peptides or peptidomimetics to probe biological systems. The fluorine atom can act as a reporter for NMR studies or alter pharmacokinetic properties of biologically active molecules.

Drug Discovery & Development

Serves as a key intermediate for synthesising novel therapeutic agents. Fluorinated amino acids are often employed to enhance drug efficacy, metabolic stability, and membrane permeability.

Organic Synthesis

Functions as a chiral building block in the synthesis of complex organic molecules beyond peptides, where the specific stereochemistry and functional groups are required.

02 /Properties

Molecular weight	283.30
Empirical formula	C14H18FNO4
Assay	≥98.0% (TLC)
Optical activity	[α]20/D −6.5±1°, c = 1% in methanol

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

114873-11-9

MDL number

MFCD00672523

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Boc-D-Phe(3-F)-OH used for?

Boc-D-Phe(3-F)-OH is primarily used as a building block in peptide synthesis, chemical biology research, and drug discovery due to its fluorinated unnatural amino acid structure.

What is the CAS number and formula for Boc-D-Phe(3-F)-OH?

The CAS number is 114873-11-9 and the empirical formula is C14H18FNO4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Boc-D-Phe(3-F)-OH with an assay of ≥98.0% (TLC). This product is intended for research and laboratory use. TSS does not represent this product as USP, BP, or EP grade.

What are the safety and handling precautions for Boc-D-Phe(3-F)-OH?

Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Please consult the Safety Data Sheet (SDS) for comprehensive information.

How is Boc-D-Phe(3-F)-OH typically packed and shipped?

This chemical is carefully packed according to international shipping regulations for hazardous materials (WGK Germany: 3) and can be exported globally by Tech Serve Solutions.

How can I request a sample or quote for Boc-D-Phe(3-F)-OH?

To request a sample or obtain a quotation, please contact our sales department via the website or direct email, providing your specific requirements and shipping details.