Boc-D-Phe(4-CF3)-OH
Boc-D-Phe(4-CF3)-OH (CAS: 82317-83-7), with the molecular formula C15H18F3NO4 and a molecular weight of 333.30 g/mol, is a trifluoromethylated D-phenylalanine derivative. This unnatural amino acid is protected with a tert-butyloxycarbonyl (Boc) group. It finds application in chemical biology, peptide synthesis, and as a building block in chemical synthesis due to its unique structural features.
- IUPAC
- Boc-4-(trifluoromethyl)-D-phenylalanine
Peptide Synthesis
Boc-D-Phe(4-CF3)-OH serves as a valuable building block in the synthesis of peptides containing unnatural amino acids. The Boc protection facilitates controlled coupling reactions, while the trifluoromethyl group can modulate peptide properties.
Chemical Biology Research
This compound is utilised in chemical biology to incorporate modified phenylalanine residues into biomolecules. Such modifications can be used to probe protein function, study molecular interactions, or develop novel biochemical tools.
Organic Synthesis Intermediate
As a specialised intermediate, Boc-D-Phe(4-CF3)-OH is employed in complex organic synthesis routes. Its trifluoromethyl and Boc functionalities offer distinct reactivity for constructing advanced molecular architectures.
| Molecular weight | 333.30 |
|---|---|
| Empirical formula | C15H18F3NO4 |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]20/D −5.4±0.7°, c = 1% in methanol |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-D-Phe(4-CF3)-OH used for?
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Boc-D-Phe(4-CF3)-OH is primarily used as a building block in peptide synthesis, chemical biology research, and as an intermediate in organic synthesis, particularly for creating peptides or molecules containing unnatural amino acid derivatives.
What is the CAS number and molecular formula for Boc-D-Phe(4-CF3)-OH?
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The CAS number for Boc-D-Phe(4-CF3)-OH is 82317-83-7, and its molecular formula is C15H18F3NO4.
What grade and purity does Tech Serve Solutions supply for Boc-D-Phe(4-CF3)-OH?
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Tech Serve Solutions supplies Boc-D-Phe(4-CF3)-OH with a purity of ≥98.0% (TLC). This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeial grades.
What are the safety and handling considerations for Boc-D-Phe(4-CF3)-OH?
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Handling Boc-D-Phe(4-CF3)-OH requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. It has a WGK Germany rating of 3, indicating a high hazard to water.
How is Boc-D-Phe(4-CF3)-OH shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and reagents, equipped to handle international shipments of products like Boc-D-Phe(4-CF3)-OH in compliance with all relevant regulations.
How can I request a sample or quote for Boc-D-Phe(4-CF3)-OH?
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To request a sample or a quotation for Boc-D-Phe(4-CF3)-OH, please contact our sales department via the website or direct email, providing your specific requirements.
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