Boc-D-Phe(4-I)-OH
Boc-D-Phe(4-I)-OH (CAS: 176199-35-2), with the molecular formula C14H18INO4, is a protected unnatural amino acid derivative. This compound is synthesised for specialised applications in chemical biology and peptide chemistry. Its structure features a D-phenylalanine core modified with a tert-butyloxycarbonyl (Boc) protecting group and an iodine atom at the para position of the phenyl ring, making it a valuable building block for complex molecular architectures.
- IUPAC
- Boc-4-iodo-D-phenylalanine
- Synonyms
- Boc-4-iodo-D-phenylalanine
Peptide Synthesis
Serves as a crucial building block in solid-phase or solution-phase peptide synthesis for incorporating unnatural amino acid residues. This allows for the creation of peptides with modified properties or novel functionalities.
Chemical Biology Research
Utilised in chemical biology to construct modified peptides or small molecules for studying biological processes. The iodine substituent can be a handle for further chemical modifications or for use in cross-coupling reactions.
Medicinal Chemistry
Employed in medicinal chemistry programmes for the design and synthesis of novel drug candidates. Its unique structure can be incorporated into lead compounds to modulate pharmacokinetic or pharmacodynamic properties.
Organic Synthesis
Acts as a chiral intermediate in complex organic synthesis, particularly where a protected, iodinated D-phenylalanine moiety is required for specific synthetic strategies.
| Molecular weight | 391.20 |
|---|---|
| Empirical formula | C14H18INO4 |
| Assay | ≥98.0% (TLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-D-Phe(4-I)-OH used for?
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Boc-D-Phe(4-I)-OH is primarily used as a building block in peptide synthesis, chemical biology research, medicinal chemistry, and complex organic synthesis. It is particularly valuable for incorporating unnatural amino acid residues with a specific modification.
What are the CAS number and formula for Boc-D-Phe(4-I)-OH?
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The CAS number is 176199-35-2 and the empirical formula is C14H18INO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-D-Phe(4-I)-OH with a purity of ≥98.0% as determined by TLC. This product is supplied for research and laboratory use and is not represented as USP, EP, BP, or pharmacopoeia grade.
How is Boc-D-Phe(4-I)-OH handled and stored safely?
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When handling Boc-D-Phe(4-I)-OH, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. Consult the Safety Data Sheet for comprehensive handling and storage instructions. The WGK Germany classification is 3, indicating a high hazard.
How are Tech Serve Solutions' chemicals packed and shipped?
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Tech Serve Solutions packs and ships fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, adhering to all necessary regulations for safe transport. Specific packaging details are determined by the quantity and nature of the chemical.
How can I request a quote or sample for Boc-D-Phe(4-I)-OH?
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To request a quote or a sample of Boc-D-Phe(4-I)-OH, please use the contact form on our website or contact our sales department directly. Our team will be pleased to assist with your inquiry.
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