Boc-D-Phg-OH
Boc-D-Phg-OH (CAS 33125-05-2) is a protected unnatural amino acid derivative, N-tert-butoxycarbonyl-D-phenylglycine. With a molecular formula of C13H17NO4 and a molecular weight of 251.28 g/mol, it is essential in chemical synthesis and peptide chemistry. This compound serves as a valuable building block for creating complex molecules and modified peptides, contributing to advancements in chemical biology research and drug discovery.
- IUPAC
- Boc-D-α-phenylglycine
- Synonyms
- N-tert-butoxycarbonyl-D-phenylglycineBoc-D-alpha-phenylglycine

Peptide Synthesis
Boc-D-Phg-OH is utilised as a key building block in the synthesis of peptides containing unnatural amino acids. Its incorporation can confer unique structural and functional properties to the resulting peptide chains.
Chemical Synthesis
This compound is a versatile reagent in organic synthesis, enabling the construction of chiral molecules. It is particularly useful for introducing the D-phenylglycine moiety into various chemical structures.
Chemical Biology Research
As an unnatural amino acid derivative, Boc-D-Phg-OH finds application in probing biological systems and developing novel biomolecules. It aids in the study of protein structure-activity relationships and the design of peptidomimetics.
| Molecular weight | 251.28 |
|---|---|
| Linear formula | C6H5CH(COOH)NHCOOC(CH3)3 |
| Assay | ≥99.0% (TLC) |
| Optical activity | [α]20/D −142.0±3.0°, c = 1% in ethanol |
| Melting point | 88-91 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-D-Phg-OH used for?
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Boc-D-Phg-OH is primarily used as a building block in peptide synthesis and organic chemical synthesis, particularly for introducing unnatural amino acid derivatives into molecules for research in chemical biology and drug discovery.
What is the CAS number and chemical formula for Boc-D-Phg-OH?
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The CAS number for Boc-D-Phg-OH is 33125-05-2, and its linear chemical formula is C6H5CH(COOH)NHCOOC(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-D-Phg-OH with a purity of ≥99.0% determined by TLC. This product is supplied for research and development purposes and is not represented as USP, EP, BP or pharmacopoeia grade.
What are the safety considerations for handling Boc-D-Phg-OH?
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When handling Boc-D-Phg-OH, it is essential to wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. Please consult the Safety Data Sheet (SDS) for comprehensive handling information.
How is Boc-D-Phg-OH typically packed and shipped?
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Boc-D-Phg-OH is carefully packed to ensure stability during transit and is available for global export. Specific packaging details will be provided with your quotation.
How can I request a sample or a quote for Boc-D-Phg-OH?
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To request a sample or a quote for Boc-D-Phg-OH, please contact our sales team through the website or by phone, providing your specific requirements.
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