Boc-D-Ser-OH
Boc-D-Ser-OH (CAS: 6368-20-3), a derivative of the amino acid D-serine, presents as a white solid with the molecular formula C8H15NO5 and a molecular weight of 205.21 g/mol. This compound is primarily utilised in peptide synthesis and chemical biology research. Its N-terminal protection with a tert-butyloxycarbonyl (Boc) group facilitates controlled peptide chain elongation, making it a valuable building block in organic and medicinal chemistry.
- IUPAC
- Boc-D-serine
- Synonyms
- Boc-D-serine

Peptide Synthesis
Boc-D-Ser-OH serves as a protected amino acid building block in solid-phase and solution-phase peptide synthesis. The Boc protecting group allows for selective deprotection and coupling reactions, enabling the construction of complex peptide sequences.
Chemical Biology
This compound is employed in chemical biology for the synthesis of modified peptides and peptidomimetics. Its incorporation can be used to study protein structure-function relationships or to develop novel biologically active molecules.
Organic Synthesis
As a chiral building block, Boc-D-Ser-OH is a useful starting material or intermediate in various organic synthesis pathways. Its defined stereochemistry is critical for producing enantiomerically pure target molecules.
| Molecular weight | 205.21 |
|---|---|
| Empirical formula | C8H15NO5 |
| Assay | ≥98.0% (TLC) |
| Optical activity | [α]20/D +3.5°, c = 2 in acetic acid |
| Melting point | 91-95 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-D-Ser-OH used for?
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Boc-D-Ser-OH is predominantly used in peptide synthesis and chemical biology research as a protected amino acid building block for constructing peptide chains and developing modified peptides.
What is the CAS number and molecular formula for Boc-D-Ser-OH?
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The CAS number for Boc-D-Ser-OH is 6368-20-3, and its molecular formula is C8H15NO5.
What grade and purity does Tech Serve Solutions supply for Boc-D-Ser-OH?
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Tech Serve Solutions supplies Boc-D-Ser-OH with an assay of ≥98.0% (TLC). This product is typically supplied as a technical or research grade, and TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling recommendations for Boc-D-Ser-OH?
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Handling Boc-D-Ser-OH requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter is recommended. The compound is classified with a WGK Germany rating of 3, indicating a significant hazard to water.
How is Boc-D-Ser-OH packed, shipped, and exported by TSS?
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Boc-D-Ser-OH is carefully packed to ensure stability during transit. Tech Serve Solutions is experienced in exporting fine chemicals globally, adhering to all necessary regulations for safe and compliant shipment.
How can I request a sample or quote for Boc-D-Ser-OH?
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To request a sample or a quote for Boc-D-Ser-OH, please contact our sales department through the website or via email, providing your specific requirements and shipping details.
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