Ethyl (3-methoxybenzoyl)acetate
Ethyl (3-methoxybenzoyl)acetate (CAS: 27834-99-7) is a specialised organic compound with the molecular formula C12H14O4 and a molecular weight of 222.24 g/mol. It serves as a versatile building block in organic synthesis, particularly in reactions involving carbonyl compounds and esters. This chemical finds application in advanced research and development, contributing to the synthesis of complex molecules through stereoselective and catalytic processes.
- IUPAC
- m-Anisoyl-acetic acid ethyl ester,Ethyl 3-(3-methoxyphenyl)-3-oxopropanoate,Ethyl m-anisoylacetate
- Synonyms
- m-Anisoyl-acetic acid ethyl esterEthyl 3-(3-methoxyphenyl)-3-oxopropanoateEthyl m-anisoylacetate
Stereoselective Ketonization-Olefination
This compound is utilised as a reactant in the stereoselective ketonization-olefination of indoles, a key transformation in heterocyclic chemistry. It facilitates precise control over stereochemical outcomes in complex organic syntheses.
Lewis Base Catalysis
Ethyl (3-methoxybenzoyl)acetate participates in Lewis base catalysed hydrosilylation and sequential reaction cascades. These processes are crucial for developing efficient synthetic methodologies and constructing intricate molecular architectures.
Asymmetric Hydrogenation
It functions as a substrate or precursor in asymmetric hydrogenation reactions, enabling the enantioselective reduction of functional groups. This is vital for producing chiral compounds with high optical purity.
Organocatalytic Reductions
The compound is employed in organocatalytic reduction processes using trichlorosilane. This method offers a sustainable approach to reduction reactions, avoiding the need for traditional metal catalysts.
| Molecular weight | 222.24 |
|---|---|
| Linear formula | CH3OC6H4COCH2CO2CH2CH3 |
| Boiling point | >268 °C(lit.) |
| Density | 1.146 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5360(lit.) |
| Application | Reactant involved in:• Stereoselective ketonization-olefination of indoles1• Lewis base catalyzed hydrosilylation2 and sequential reactions3,4• Asymmetric hydrogenation5• Organocatalytic reduction by trichlorosilane6 |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl (3-methoxybenzoyl)acetate used for?
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Ethyl (3-methoxybenzoyl)acetate is primarily used as a reactant and building block in various organic synthesis applications, including stereoselective ketonization-olefination of indoles, Lewis base catalysed reactions, asymmetric hydrogenation, and organocatalytic reductions.
What is the CAS number and molecular formula for Ethyl (3-methoxybenzoyl)acetate?
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The CAS number for Ethyl (3-methoxybenzoyl)acetate is 27834-99-7, and its linear molecular formula is CH3OC6H4COCH2CO2CH2CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl (3-methoxybenzoyl)acetate typically as a research or technical grade chemical. The specific assay and purity details are available on the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for Ethyl (3-methoxybenzoyl)acetate?
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For safe handling, it is recommended to wear eyeshields and gloves. The compound is classified under WGK 3 in Germany, indicating a hazard to water. Please refer to the Safety Data Sheet (SDS) for comprehensive hazard information and handling procedures.
How is Ethyl (3-methoxybenzoyl)acetate packed, shipped, and exported?
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Ethyl (3-methoxybenzoyl)acetate is carefully packed to ensure stability during transit and is exported globally by Tech Serve Solutions in compliance with all relevant shipping regulations for chemical substances.
How can I request a sample or a quote for Ethyl (3-methoxybenzoyl)acetate?
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To request a sample or a quote for Ethyl (3-methoxybenzoyl)acetate, please contact our sales department through the website or by phone, providing your specific requirements and shipping details.
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