Boc-D-Phe-OH

CAS 18942-49-9C14H19NO4Chemical Synthesis

Boc-D-Phe-OH (CAS 18942-49-9) is a protected amino acid derivative with the molecular formula C14H19NO4. As a key building block in peptide synthesis, it facilitates controlled coupling reactions. Its D-configuration is particularly valuable for creating non-natural peptide structures with unique biological or chemical properties, finding applications in pharmaceutical research and chemical biology.

IUPAC: Boc-D-phenylalanine
Synonyms: N-(tert-Butoxycarbonyl)-D-phenylalanine

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Boc-D-Phe-OH (C14H19NO4) — chemical structure, CAS 18942-49-9; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesChemical BiologyChemical SynthesisPeptide ChemistryPhenylalanine

01 /Applications

Peptide Synthesis

Used as a protected amino acid for incorporating D-phenylalanine residues into peptide chains. The Boc protecting group allows for selective deprotection under mild acidic conditions during solid-phase or solution-phase synthesis.

Chemical Biology

Serves as a crucial intermediate in the synthesis of modified peptides and peptidomimetics for biological studies. Its incorporation can alter peptide conformation and stability, aiding in the investigation of protein-ligand interactions.

Chemical Synthesis

Acts as a chiral building block in the synthesis of complex organic molecules where a D-phenylalanine moiety is required. It is valuable for creating stereochemically defined targets in drug discovery and materials science.

02 /Properties

Molecular weight	265.30
Empirical formula	C14H19NO4
Assay	≥99.0% (sum of enantiomers, TLC)
Optical activity	[α]20/D −25±1°, c = 1% in ethanol
Storage temperature	2-8°C
Melting point	78-87 °C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

18942-49-9

MDL number

MFCD00063149

Beilstein registry

4695945

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Boc-D-Phe-OH used for?

Boc-D-Phe-OH is primarily used as a protected amino acid in peptide synthesis, chemical biology, and general chemical synthesis for creating modified peptides and complex organic molecules.

What are the CAS number and formula for Boc-D-Phe-OH?

The CAS number for Boc-D-Phe-OH is 18942-49-9 and its molecular formula is C14H19NO4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Boc-D-Phe-OH with an assay of ≥99.0% (sum of enantiomers, TLC). TSS does not represent this product as USP, BP, or EP grade.

How should Boc-D-Phe-OH be handled and stored?

Handle Boc-D-Phe-OH with appropriate personal protective equipment, including eyeshields and gloves. It should be stored at 2-8°C. Users should consult the safety data sheet for detailed handling information.

Is Boc-D-Phe-OH a controlled substance?

Based on the provided data, Boc-D-Phe-OH is not listed as a controlled substance. Standard chemical handling procedures are recommended.

How can I request a sample or quote for Boc-D-Phe-OH?

To request a sample or quote, please contact our sales department through the website or direct inquiry channels, specifying product name and CAS number.

How is Boc-D-Phe-OH shipped?

Boc-D-Phe-OH is typically shipped under refrigerated conditions (2-8°C) to maintain its quality. We are a global supplier and exporter of fine chemicals.