Boc-D-Phe(4-Cl)-OH
Boc-D-Phe(4-Cl)-OH (CAS: 57292-44-1) is a protected unnatural amino acid derivative with the empirical formula C14H18ClNO4 and a molecular weight of 299.75 g/mol. This compound is primarily utilised in chemical biology and peptide chemistry for the synthesis of complex peptides and peptidomimetics. Its structure, featuring a Boc protecting group and a para-chlorinated phenylalanine core, makes it a valuable building block in drug discovery and biochemical research.
- IUPAC
- Boc-4-chloro-D-phenylalanine
- Synonyms
- Boc-4-chloro-D-phenylalanine

Peptide Synthesis
Serves as a protected unnatural amino acid building block for incorporating modified phenylalanine residues into peptide chains. Useful in creating peptides with altered biological activity or stability.
Chemical Biology Research
Employed in studies involving protein structure, function, and interactions. The unnatural amino acid can be used to probe biological systems or create novel biomolecules.
Drug Discovery Intermediate
A key intermediate in the synthesis of potential pharmaceutical agents. Its unique structure can contribute to the development of novel therapeutic candidates.
Organic Synthesis
Utilised as a chiral building block in complex organic synthesis pathways. Enables the construction of stereochemically defined molecules.
| Molecular weight | 299.75 |
|---|---|
| Empirical formula | C14H18ClNO4 |
| Assay | ≥96.0% |
| Optical activity | [α]20/D −26±2°, c = 1% in ethyl acetate |
| Melting point | ~110 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-D-Phe(4-Cl)-OH used for?
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Boc-D-Phe(4-Cl)-OH is primarily used as a building block in peptide synthesis, chemical biology research, and as an intermediate in drug discovery and organic synthesis due to its protected unnatural amino acid structure.
What is the CAS number and formula for Boc-D-Phe(4-Cl)-OH?
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The CAS number is 57292-44-1 and the empirical formula is C14H18ClNO4.
What grade and purity does Tech Serve Solutions supply for Boc-D-Phe(4-Cl)-OH?
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Tech Serve Solutions supplies Boc-D-Phe(4-Cl)-OH with an assay of ≥96.0%. This product is not supplied as USP, BP, or EP grade.
How should Boc-D-Phe(4-Cl)-OH be handled?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Users should consult the Safety Data Sheet for full handling and hazard information.
Is Boc-D-Phe(4-Cl)-OH suitable for pharmaceutical manufacturing?
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Boc-D-Phe(4-Cl)-OH is supplied with an assay of ≥96.0% and is not classified as USP, BP, or EP grade. Its use in pharmaceutical manufacturing requires appropriate validation and quality control.
How is Boc-D-Phe(4-Cl)-OH shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, capable of handling international shipments of Boc-D-Phe(4-Cl)-OH in compliance with relevant regulations.
How can I request a quote or sample for Boc-D-Phe(4-Cl)-OH?
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To request a quote or sample, please contact our sales team through the Tech Serve Solutions website or directly via the provided contact information.
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