Boc-D-Phe(4-NO2)-OH
Boc-D-Phe(4-NO2)-OH (CAS: 61280-75-9), with the molecular formula C14H18N2O6, is a protected amino acid derivative. This compound serves as a valuable building block in chemical synthesis and peptide chemistry. Its structure, featuring a nitro group on the phenylalanine ring and a Boc protecting group, makes it particularly useful for incorporating modified amino acid residues into peptides and for various research applications in chemical biology.
- IUPAC
- Boc-4-nitro-D-phenylalanine
- Synonyms
- Boc-4-nitro-D-phenylalanine

Peptide Synthesis
Boc-D-Phe(4-NO2)-OH is used as a key intermediate in the synthesis of peptides. It allows for the introduction of a nitro-substituted D-phenylalanine residue, which can be crucial for studying peptide structure-activity relationships or for developing novel peptide-based therapeutics.
Chemical Biology Research
This compound finds application in chemical biology for constructing peptides with specific functionalities. The nitro group can serve as a handle for further chemical modifications or as a probe in biological systems.
Synthesis of Novel Compounds
Beyond peptide synthesis, Boc-D-Phe(4-NO2)-OH can be employed in the broader field of organic synthesis for creating complex molecules and unnatural amino acid derivatives for various research purposes.
| Molecular weight | 310.30 |
|---|---|
| Empirical formula | C14H18N2O6 |
| Assay | ≥98.0% (TLC) |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-D-Phe(4-NO2)-OH used for?
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Boc-D-Phe(4-NO2)-OH is primarily used as a building block in peptide synthesis and in chemical biology research for introducing nitro-substituted D-phenylalanine residues into molecules.
What are the CAS number and molecular formula for Boc-D-Phe(4-NO2)-OH?
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The CAS number for Boc-D-Phe(4-NO2)-OH is 61280-75-9, and its molecular formula is C14H18N2O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-D-Phe(4-NO2)-OH with an assay of ≥98.0% (TLC). TSS does not represent this product as USP, BP, or EP grade.
How should Boc-D-Phe(4-NO2)-OH be handled and stored?
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Handle Boc-D-Phe(4-NO2)-OH with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. It should be stored at 2-8°C.
Is Boc-D-Phe(4-NO2)-OH a hazardous substance?
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According to the supplied data, Boc-D-Phe(4-NO2)-OH has a WGK Germany rating of 3, indicating it is a substance that poses a significant hazard to water. Appropriate safety precautions must be taken during handling and disposal.
How is Boc-D-Phe(4-NO2)-OH shipped and exported?
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Tech Serve Solutions, established in 1998, is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, adhering to all necessary regulations for international shipment.
How can I request a sample or quote for Boc-D-Phe(4-NO2)-OH?
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Please contact our sales team directly through our website or by phone to request a sample or a quotation for Boc-D-Phe(4-NO2)-OH.
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