Boc-D-Phe(2-Me)-OH
Boc-D-Phe(2-Me)-OH (CAS: 80102-29-0) is a protected, unnatural amino acid derivative with the molecular formula C15H21NO4 and a molecular weight of 279.33 g/mol. It is primarily utilised in chemical synthesis and peptide chemistry as a building block. This compound serves as a valuable intermediate in the development of novel peptides and peptidomimetics, contributing to advancements in chemical biology.
- IUPAC
- Boc-2-methyl-D-phenylalanine
- Synonyms
- Boc-2-methyl-D-phenylalanine

Peptide Synthesis
This N-terminally protected D-phenylalanine derivative serves as a crucial building block in solid-phase and solution-phase peptide synthesis. Its unnatural structure allows for the introduction of specific conformational constraints or functionalities into peptide sequences.
Chemical Biology Research
Boc-D-Phe(2-Me)-OH is employed in chemical biology to create modified peptides for studying protein-protein interactions, enzyme mechanisms, and drug discovery. The incorporation of unnatural amino acids can enhance stability or alter biological activity.
Medicinal Chemistry
It acts as an intermediate in medicinal chemistry for the synthesis of novel drug candidates. The unique structural features of this unnatural amino acid can be leveraged to design molecules with improved pharmacokinetic properties or targeted therapeutic effects.
| Molecular weight | 279.33 |
|---|---|
| Empirical formula | C15H21NO4 |
| Assay | ≥98.0% (TLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-D-Phe(2-Me)-OH used for?
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Boc-D-Phe(2-Me)-OH is used in chemical synthesis, peptide chemistry, and chemical biology research as a building block for creating modified peptides and other complex organic molecules.
What are the CAS number and molecular formula for Boc-D-Phe(2-Me)-OH?
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The CAS number for Boc-D-Phe(2-Me)-OH is 80102-29-0, and its molecular formula is C15H21NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-D-Phe(2-Me)-OH with an assay of ≥98.0% (TLC). This product is supplied for research and chemical synthesis purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling considerations for Boc-D-Phe(2-Me)-OH?
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Boc-D-Phe(2-Me)-OH requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It carries a WGK Germany rating of 3, indicating it is hazardous to water.
How is Boc-D-Phe(2-Me)-OH packed and shipped?
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Tech Serve Solutions professionally packs and ships chemicals globally, adhering to all necessary regulations for safe transport and export.
How can I request a quote or sample for Boc-D-Phe(2-Me)-OH?
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You can request a quote or sample by contacting our sales team through the website or by calling our dedicated customer service line.
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