Bis(4-fluorophenyl)iodonium triflate
Bis(4-fluorophenyl)iodonium triflate (CAS 732306-64-8) is a hypervalent iodine compound with the molecular formula C13H8F5IO3S and a molecular weight of 466.16 g/mol. This diaryliodonium salt serves as a versatile reagent in organic synthesis, particularly as an efficient electrophilic trifluoromethylating agent and in cross-coupling reactions. Its application facilitates the introduction of fluorinated moieties into various organic structures.
- IUPAC
- (p-F-Ph)2IOTf,Bis(4-fluorophenyl)iodonium trifluoromethanesulfonate
Electrophilic Trifluoromethylation
This compound is employed as a source of the trifluoromethyl group (CF3) in electrophilic trifluoromethylation reactions. It allows for the efficient introduction of CF3 substituents onto nucleophilic substrates, such as enolates and heteroatoms.
Cross-Coupling Reactions
Bis(4-fluorophenyl)iodonium triflate can participate in various transition-metal-catalysed cross-coupling reactions. It enables the formation of carbon-carbon and carbon-heteroatom bonds, expanding its utility in complex molecule synthesis.
Synthetic Reagent in Organic Synthesis
As a hypervalent iodine reagent, it offers a convenient and often milder alternative to traditional methods for oxidation and functionalisation. Its unique reactivity profile makes it valuable for various transformations in medicinal chemistry and materials science.
| Molecular weight | 466.16 |
|---|---|
| Empirical formula | C13H8F5IO3S |
| Assay | ≥98% (HPLC) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Bis(4-fluorophenyl)iodonium triflate primarily used for?
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Bis(4-fluorophenyl)iodonium triflate is primarily used as an electrophilic trifluoromethylating agent and in cross-coupling reactions within organic synthesis.
What is the CAS number and molecular formula for Bis(4-fluorophenyl)iodonium triflate?
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The CAS number is 732306-64-8 and the molecular formula is C13H8F5IO3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Bis(4-fluorophenyl)iodonium triflate with an assay of ≥98% (HPLC). This is a technical/research grade product, and we do not represent it as USP, BP, EP, or any pharmacopoeia grade.
What are the main safety hazards associated with this chemical?
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This compound is classified as a Warning with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment and handling procedures are essential.
How is this chemical typically packed and shipped?
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Products are carefully packed to ensure stability and safety during transit. We are experienced in exporting fine chemicals globally.
How can I request a sample or obtain a quote?
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Please contact our sales team directly via the website or by phone to request a sample or obtain a quotation for Bis(4-fluorophenyl)iodonium triflate.
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