2-(Trifluoromethyl)pyrrolidine
2-(Trifluoromethyl)pyrrolidine (CAS: 109074-67-1; Formula: C5H8F3N; Molar Mass: 139.12 g/mol) is a heterocyclic building block incorporating a trifluoromethyl group onto a pyrrolidine ring. This fluorinated amine derivative is valuable in organic synthesis, particularly for introducing trifluoromethylated fragments into more complex molecules. It finds application in the development of novel chemical entities and advanced materials.
Fluorinated Building Block
Utilised as a key intermediate in the synthesis of complex organic molecules, particularly where the incorporation of a trifluoromethyl group is desired. Its structure allows for diverse chemical transformations in the development of new compounds.
Pharmaceutical Intermediate
Serves as a valuable component in the research and development of new pharmaceutical agents. The trifluoromethyl group can significantly influence the pharmacokinetic and pharmacodynamic properties of drug candidates.
Agrochemical Synthesis
Employable in the creation of novel agrochemicals, where fluorinated moieties can enhance efficacy and stability. It contributes to the structural diversity of crop protection agents.
Materials Science
Can be incorporated into the synthesis of advanced materials, leveraging the unique properties conferred by the trifluoromethyl substituent, such as altered solubility or electronic characteristics.
| Molecular weight | 139.12 |
|---|---|
| Empirical formula | C5H8F3N |
| Assay | 97% |
| Boiling point | 104-106 °C |
| Density | 1.210 g/mL at 25 °C |
| Refractive index | n20/D 1.379 |
| Storage temperature | 2-8°C |
Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 26 °C / 78.8 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trifluoromethyl)pyrrolidine primarily used for?
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2-(Trifluoromethyl)pyrrolidine is primarily used as a building block in organic synthesis, particularly for introducing trifluoromethylated fragments into more complex molecules, finding applications in pharmaceuticals, agrochemicals, and materials science.
What is the CAS number and chemical formula for 2-(Trifluoromethyl)pyrrolidine?
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The CAS number for 2-(Trifluoromethyl)pyrrolidine is 109074-67-1, and its chemical formula is C5H8F3N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Trifluoromethyl)pyrrolidine with a minimum assay of 97%. This product is supplied for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should 2-(Trifluoromethyl)pyrrolidine be handled safely?
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2-(Trifluoromethyl)pyrrolidine is flammable and harmful if swallowed, causing skin and eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including eyeshields, gloves, and use in a well-ventilated area or fume hood. Refer to the Safety Data Sheet for comprehensive handling instructions.
Is 2-(Trifluoromethyl)pyrrolidine available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-(Trifluoromethyl)pyrrolidine, adhering to all relevant international shipping regulations.
How can I request a quote or sample for 2-(Trifluoromethyl)pyrrolidine?
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To request a quote or sample, please visit the product page on our website and use the 'Request a Quote' or 'Request a Sample' function, or contact our sales team directly.
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