2-(Trifluoromethyl)pyridine-3-carboxylic acid
2-(Trifluoromethyl)pyridine-3-carboxylic acid (CAS: 131747-43-8), with the molecular formula C7H4F3NO2 and a molecular weight of 191.11 g/mol, is a key building block in organic synthesis. This halogenated heterocyclic compound is primarily employed in the development of novel pharmaceuticals and agrochemicals. Its trifluoromethyl and carboxylic acid functionalities offer versatile reactivity for constructing complex molecular architectures, making it an essential reagent for advanced chemical research and development.
- IUPAC
- 2-(Trifluoromethyl)nicotinic acid
Pharmaceutical Intermediate
Utilised as a critical intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its structure facilitates the incorporation of the trifluoromethyl pyridine moiety into drug candidates targeting various therapeutic areas.
Agrochemical Synthesis
Serves as a valuable building block for the creation of novel pesticides, herbicides, and fungicides. The trifluoromethyl group often imparts enhanced biological activity and stability to agrochemical compounds.
Materials Science
Can be employed in the development of specialised organic materials and polymers where the electronic or physical properties conferred by the fluorinated pyridine ring are desired.
Research and Development
A versatile reagent for academic and industrial research laboratories exploring new synthetic methodologies and target molecules within medicinal chemistry and organic synthesis.
| Molecular weight | 191.11 |
|---|---|
| Empirical formula | C7H4F3NO2 |
| Assay | 96% |
| Melting point | 184-188 °C |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trifluoromethyl)pyridine-3-carboxylic acid used for?
+
This compound is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It is also utilised in materials science and general chemical research.
What are the CAS number and molecular formula?
+
The CAS number is 131747-43-8, and the molecular formula is C7H4F3NO2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-(Trifluoromethyl)pyridine-3-carboxylic acid with a minimum assay of 96%. This product is intended for research and chemical synthesis purposes; TSS does not represent it as USP, BP, EP, or any other pharmacopoeial grade.
What are the primary safety concerns when handling this chemical?
+
This compound is classified as toxic if swallowed (H301) and requires careful handling. Always use appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, faceshields, and gloves. Ensure adequate ventilation and follow precautionary statements (P301 + P310).
Does Tech Serve Solutions export this chemical?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-(Trifluoromethyl)pyridine-3-carboxylic acid, serving customers worldwide.
How can I request a quote or sample?
+
To request a quote or sample of 2-(Trifluoromethyl)pyridine-3-carboxylic acid, please contact our sales department through the website or via email, providing your contact details and quantity requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis