2-(Trifluoromethyl)pyrazine
2-(Trifluoromethyl)pyrazine (CAS: 61655-67-2), with the molecular formula C5H3F3N2 and a molecular weight of 148.09 g/mol, is a valuable heterocyclic building block. This fluorinated pyrazine derivative is primarily utilised in chemical synthesis, offering a unique structural motif for the development of novel compounds. Its characteristics make it a useful intermediate in various research and development applications within the chemical industry.

Pharmaceutical Intermediate
Serves as a building block in the synthesis of complex organic molecules, potentially contributing to the development of new pharmaceutical agents.
Agrochemical Research
The trifluoromethylpyrazine scaffold can be incorporated into the design of novel agrochemicals, aiding in the discovery of new crop protection agents.
Materials Science
Utilised in research for developing new materials with specific electronic or optical properties, leveraging the unique characteristics of the fluorinated heterocycle.
Organic Synthesis Reagent
A versatile reagent for introducing the trifluoromethylpyrazine moiety into larger molecular structures during complex organic synthesis procedures.
| Molecular weight | 148.09 |
|---|---|
| Empirical formula | C5H3F3N2 |
| Assay | 97% |
| Density | 1.344 g/mL at 25 °C |
| Refractive index | n20/D 1.417 |


Hazard statements
- H226Flammable liquid and vapour
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Flash point | 33 °C / 91.4 °F |
|---|---|
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | T |
| Risk statements (R) | 10-25-36/37/38 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trifluoromethyl)pyrazine used for?
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2-(Trifluoromethyl)pyrazine is used as a building block in chemical synthesis, particularly for developing novel compounds in pharmaceutical and agrochemical research, as well as in materials science.
What is the CAS number and formula for 2-(Trifluoromethyl)pyrazine?
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The CAS number is 61655-67-2 and the empirical formula (Hill notation) is C5H3F3N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Trifluoromethyl)pyrazine with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 2-(Trifluoromethyl)pyrazine be handled safely?
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This compound is classified as Danger, is flammable (H226) and toxic if swallowed (H301). It is also irritating to skin, eyes, and respiratory tract (H315, H319, H335). Handle with appropriate personal protective equipment in a well-ventilated area, avoiding ignition sources.
Is 2-(Trifluoromethyl)pyrazine a controlled substance?
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Based on the provided safety data (Hazard Code Europe: T, Risk Statements: 25), it is classified as toxic, but it is not indicated as a controlled substance in this data.
How is 2-(Trifluoromethyl)pyrazine shipped?
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Tech Serve Solutions exports fine chemicals globally. Specific shipping and packaging details will be provided upon order confirmation, adhering to all transport regulations.
How can I request a sample or quote for 2-(Trifluoromethyl)pyrazine?
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To request a sample or quote, please contact our sales team through the website or via direct inquiry, providing your specific requirements.
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