2-(Trifluoromethyl)piperidine
2-(Trifluoromethyl)piperidine (CAS: 154630-93-0; Formula: C6H10F3N) is a fluorinated heterocyclic compound with a molecular weight of 153.15 g/mol. It serves as a valuable building block in organic synthesis, particularly for introducing the trifluoromethylpiperidine moiety into more complex molecules. Its unique structure makes it useful in the development of novel pharmaceuticals and agrochemicals.
Pharmaceutical Synthesis
This compound acts as a crucial intermediate in the synthesis of active pharmaceutical ingredients (APIs). The incorporation of the trifluoromethyl group often enhances metabolic stability and lipophilicity, key factors in drug design.
Agrochemical Development
It is utilised in the creation of new pesticides and herbicides. The fluorinated nature of the molecule can impart desirable properties such as increased efficacy and environmental persistence.
Material Science Research
The unique properties of fluorinated organic compounds like 2-(Trifluoromethyl)piperidine make them potential candidates for specialised material applications and research into novel polymers.
Organic Synthesis Reagent
As a functionalised heterocycle, it is employed in diverse organic transformations, enabling chemists to construct complex molecular architectures with precision.
| Molecular weight | 153.15 |
|---|---|
| Empirical formula | C6H10F3N |
| Assay | 97% |
| Density | 1.126 g/mL at 25 °C |
| Refractive index | n20/D 1.390 |
Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H400Very toxic to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P305IF IN EYES
| Flash point | 27 °C / 80.6 °F |
|---|---|
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 10-22-36/37/38-50 |
| Safety statements (S) | 26-36/37/39-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trifluoromethyl)piperidine used for?
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2-(Trifluoromethyl)piperidine is primarily used as a building block in organic synthesis for the development of pharmaceuticals, agrochemicals, and potentially novel materials. It facilitates the introduction of a trifluoromethylpiperidine functional group into target molecules.
What are the CAS number and chemical formula for 2-(Trifluoromethyl)piperidine?
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The CAS number for 2-(Trifluoromethyl)piperidine is 154630-93-0, and its chemical formula is C6H10F3N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Trifluoromethyl)piperidine with an assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 2-(Trifluoromethyl)piperidine be handled safely?
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2-(Trifluoromethyl)piperidine is a flammable liquid and vapour (H226) and is harmful if swallowed (H302), causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). It is also very toxic to aquatic life with long-lasting effects (H400). Handle with appropriate personal protective equipment in a well-ventilated area, avoiding ignition sources and release into the environment. Always consult the Safety Data Sheet (SDS) before use.
Is 2-(Trifluoromethyl)piperidine a controlled substance?
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The provided data does not indicate that 2-(Trifluoromethyl)piperidine is a controlled substance.
How is 2-(Trifluoromethyl)piperidine packed and shipped?
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Tech Serve Solutions packs and ships chemicals in compliance with international regulations for hazardous materials. Specific packaging details are available upon request.
How can I request a quote or sample for 2-(Trifluoromethyl)piperidine?
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To request a quote or sample for 2-(Trifluoromethyl)piperidine, please contact our sales department through the website or by phone.
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