2-(Trifluoromethyl)pyridine
2-(Trifluoromethyl)pyridine (CAS: 368-48-9; Formula: C6H4F3N; Mol. Wt.: 147.10) is a valuable fluorinated heterocyclic building block used in chemical synthesis. Its unique trifluoromethyl group imparts specific electronic and lipophilic properties, making it a sought-after intermediate. Available with an assay of 97%, it is supplied by Tech Serve Solutions for various research and development applications in organic chemistry and materials science.
- IUPAC
- α,α,α-Trifluoro-2-picoline
Organic Synthesis Intermediate
This compound serves as a versatile building block in the synthesis of more complex organic molecules. The trifluoromethylpyridine moiety can be incorporated into various target structures, offering unique electronic and steric properties.
Pharmaceutical Research
It is utilised in the development of novel pharmaceutical agents. The incorporation of fluorine atoms, particularly as a trifluoromethyl group, is a common strategy in medicinal chemistry to enhance metabolic stability and binding affinity.
Agrochemical Development
The unique properties of 2-(trifluoromethyl)pyridine make it a useful component in the design and synthesis of new agrochemicals, including pesticides and herbicides, where enhanced efficacy and targeted action are desired.
Materials Science
This pyridine derivative can be employed in the synthesis of advanced materials, such as functional polymers or electronic components, where its specific chemical and physical characteristics are beneficial.
| Molecular weight | 147.10 |
|---|---|
| Empirical formula | C6H4F3N |
| Assay | 97% |
| Boiling point | 139-141 °C |
| Density | 1.275 g/mL at 25 °C |
| Refractive index | n20/D 1.419 |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 42 °C / 107.6 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trifluoromethyl)pyridine used for?
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2-(Trifluoromethyl)pyridine is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials due to the unique properties conferred by the trifluoromethyl group.
What is the CAS number and formula for 2-(Trifluoromethyl)pyridine?
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The CAS number for 2-(Trifluoromethyl)pyridine is 368-48-9, and its empirical formula is C6H4F3N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Trifluoromethyl)pyridine with a minimum assay of 97%. This product is intended for research and synthesis purposes and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 2-(Trifluoromethyl)pyridine be handled safely?
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Handling 2-(Trifluoromethyl)pyridine requires appropriate personal protective equipment, including eyeshields, face shields, and gloves. Ensure adequate ventilation and use a suitable respirator cartridge, as it is flammable and can cause skin, eye, and respiratory irritation (H226-H315-H319-H335).
How is 2-(Trifluoromethyl)pyridine packed and shipped?
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As a global supplier and exporter, Tech Serve Solutions adheres to strict regulations for packing and shipping chemicals like 2-(Trifluoromethyl)pyridine (UN 1993C 3 / PGIII), ensuring safe and compliant delivery worldwide.
How can I request a sample or quote for 2-(Trifluoromethyl)pyridine?
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To request a sample or obtain a quote for 2-(Trifluoromethyl)pyridine, please contact our sales team through the website or directly via email, providing your specific requirements.
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