2-(Trifluoromethyl)piperidine hydrochloride
2-(Trifluoromethyl)piperidine hydrochloride (CAS 627533-08-8) is a fluorinated heterocyclic compound with the molecular formula C6H10F3N · HCl and a molecular weight of 189.61 g/mol. It serves as a valuable building block in organic synthesis, particularly within the C5 to C7 carbon range. Its trifluoromethyl group offers unique electronic properties, making it useful in the development of novel chemical entities for research and development purposes.

Organic Synthesis Intermediate
This compound is employed as a key intermediate in the synthesis of more complex organic molecules. Its structure, featuring a piperidine ring substituted with a trifluoromethyl group, allows for diverse chemical transformations.
Pharmaceutical Research
It acts as a building block in the exploration of new pharmaceutical candidates. The incorporation of trifluoromethyl groups can modulate pharmacokinetic properties such as lipophilicity and metabolic stability.
Agrochemical Development
The unique properties conferred by the trifluoromethyl moiety make this compound potentially useful in the design and synthesis of novel agrochemicals.
Material Science Research
Its specific chemical structure may be leveraged in the development of new materials with tailored properties.
| Molecular weight | 189.61 |
|---|---|
| Empirical formula | C6H10F3N · HCl |
| Assay | ≥96.0%96.0-104.0% |

Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trifluoromethyl)piperidine hydrochloride used for?
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2-(Trifluoromethyl)piperidine hydrochloride is primarily used as a building block in organic synthesis, particularly in the development of new pharmaceutical and agrochemical compounds. Its trifluoromethyl group imparts unique electronic and physical properties.
What is the CAS number and formula for 2-(Trifluoromethyl)piperidine hydrochloride?
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The CAS number is 627533-08-8, and the empirical formula is C6H10F3N · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Trifluoromethyl)piperidine hydrochloride with an assay of ≥96.0% (96.0-104.0%). We do not represent this product as USP, BP, or EP grade.
How should 2-(Trifluoromethyl)piperidine hydrochloride be handled?
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Handle with care. This compound is toxic if swallowed and causes skin and eye irritation, and may cause respiratory irritation (H301-H315-H319-H335). Use appropriate personal protective equipment including a dust mask (type N95), eyeshields, faceshields, and gloves. Ensure adequate ventilation and avoid dust formation.
Is 2-(Trifluoromethyl)piperidine hydrochloride a controlled substance?
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This information is not available in the provided data. Please consult relevant regulatory lists for controlled substance status.
How is 2-(Trifluoromethyl)piperidine hydrochloride packed and shipped?
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Tech Serve Solutions packs and exports chemicals in compliance with all relevant international shipping regulations. Specific packaging details can be provided upon request.
How can I request a sample or quote for 2-(Trifluoromethyl)piperidine hydrochloride?
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To request a sample or quote, please use the contact form on our website or contact our sales team directly with your inquiry.
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