2-(Trifluoromethyl)phenylhydrazine
2-(Trifluoromethyl)phenylhydrazine (CAS: 365-34-4) is an organic compound with the linear formula CF3C6H4NHNH2 and a molecular weight of 176.14 g/mol. This hydrazine derivative serves as a valuable intermediate in organic synthesis. Its primary utility lies in the preparation of biologically active azole and aminoguanidine derivatives, making it a key building block for the pharmaceutical and fine chemical industries.
Azole Synthesis
This compound is an effective intermediate for synthesising various biologically active azole compounds. These structures are frequently found in pharmaceuticals and agrochemicals.
Aminoguanidine Derivative Preparation
It is employed in the preparation of aminoguanidine derivatives. These molecules can exhibit diverse biological activities, contributing to drug discovery efforts.
Organic Synthesis Building Block
As a functionalised hydrazine, 2-(Trifluoromethyl)phenylhydrazine acts as a versatile building block in complex organic synthesis pathways. It allows for the introduction of specific trifluoromethylphenylhydrazine moieties.
| Molecular weight | 176.14 |
|---|---|
| Linear formula | CF3C6H4NHNH2 |
| Assay | 97% |
| Application | A useful intermediate employed in the preparation of biologically active azoles1,2 and aminoguanidine derivatives.3 |
| Melting point | 56-60 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trifluoromethyl)phenylhydrazine used for?
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2-(Trifluoromethyl)phenylhydrazine is primarily used as an intermediate in the synthesis of biologically active azole and aminoguanidine derivatives. It is a valuable building block in organic synthesis.
What is the CAS number and formula for 2-(Trifluoromethyl)phenylhydrazine?
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The CAS number is 365-34-4, and the linear formula is CF3C6H4NHNH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Trifluoromethyl)phenylhydrazine with an assay of 97%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should 2-(Trifluoromethyl)phenylhydrazine be handled safely?
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2-(Trifluoromethyl)phenylhydrazine is a Warning substance that can cause harm if swallowed (H302) and leads to skin (H315), eye (H319), and respiratory tract irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be worn. Ensure adequate ventilation.
Does Tech Serve Solutions export 2-(Trifluoromethyl)phenylhydrazine?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-(Trifluoromethyl)phenylhydrazine.
How can I request a quote or sample?
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To request a quote or sample of 2-(Trifluoromethyl)phenylhydrazine, please contact our sales team through the website or by phone.
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