2-(Trifluoromethyl)phenylacetic acid
2-(Trifluoromethyl)phenylacetic acid (CAS: 3038-48-0), with the molecular formula CF3C6H4CH2CO2H and a molar mass of 204.15 g/mol, is a valuable organic building block. This carboxylic acid is utilised in chemical synthesis, particularly in the development of potential pharmaceutical agents. Its trifluoromethylphenyl structure makes it a useful intermediate for introducing specific functional groups into target molecules.
- IUPAC
- (α,α,α-Trifluoro-o-tolyl)acetic acid
- Synonyms
- (α,α,α-Trifluoro-o-tolyl)acetic acid

Synthesis of Antithrombotics
2-(Trifluoromethyl)phenylacetic acid has been employed in the synthetic pathways for novel antithrombotic compounds. These studies explore its utility in developing agents that may help prevent blood clot formation.
Development of Lipoxygenase Inhibitors
Research indicates the use of this compound in synthesising potential lipoxygenase inhibitors. These molecules are investigated for their role in modulating inflammatory pathways.
Organic Synthesis Intermediate
As a versatile building block, 2-(Trifluoromethyl)phenylacetic acid serves as a key intermediate in various organic synthesis projects. Its structure allows for further functionalisation in complex molecule construction.
| Molecular weight | 204.15 |
|---|---|
| Linear formula | CF3C6H4CH2CO2H |
| Assay | 98% |
| Application | 2-(Trifluoromethyl)phenylacetic acid has been used in the synthesis of potential antithrombotics1 and lipoxygenase inhibitors2. |
| Melting point | 100-102 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trifluoromethyl)phenylacetic acid used for?
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2-(Trifluoromethyl)phenylacetic acid is used as a building block in organic synthesis, including the development of potential antithrombotics and lipoxygenase inhibitors.
What are the CAS number and molecular formula for 2-(Trifluoromethyl)phenylacetic acid?
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The CAS number is 3038-48-0 and the molecular formula is CF3C6H4CH2CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Trifluoromethyl)phenylacetic acid with a purity of 98%. We do not represent this product as USP, BP, or EP grade.
How should 2-(Trifluoromethyl)phenylacetic acid be handled safely?
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Handling requires appropriate personal protective equipment including a dust mask (N95 type), eyeshields, and gloves. Ensure good ventilation and avoid breathing dust. It is classified as a warning substance with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335).
Does Tech Serve Solutions export 2-(Trifluoromethyl)phenylacetic acid?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-(Trifluoromethyl)phenylacetic acid.
How can I request a sample or quote for 2-(Trifluoromethyl)phenylacetic acid?
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Please contact our sales team via the website or by phone to request a sample or obtain a quotation for 2-(Trifluoromethyl)phenylacetic acid.
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