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2-(Trifluoromethyl)phenylacetic acid

CAS 3038-48-0CF3C6H4CH2CO2HChemical Synthesis

2-(Trifluoromethyl)phenylacetic acid (CAS: 3038-48-0), with the molecular formula CF3C6H4CH2CO2H and a molar mass of 204.15 g/mol, is a valuable organic building block. This carboxylic acid is utilised in chemical synthesis, particularly in the development of potential pharmaceutical agents. Its trifluoromethylphenyl structure makes it a useful intermediate for introducing specific functional groups into target molecules.

IUPAC
(α,α,α-Trifluoro-o-tolyl)acetic acid
Synonyms
(α,α,α-Trifluoro-o-tolyl)acetic acid
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2-(Trifluoromethyl)phenylacetic acid (CF3C6H4CH2CO2H) — chemical structure, CAS 3038-48-0; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksCarbonyl CompoundsCarboxylic AcidsChemical Synthesis
01 /Applications

Synthesis of Antithrombotics

2-(Trifluoromethyl)phenylacetic acid has been employed in the synthetic pathways for novel antithrombotic compounds. These studies explore its utility in developing agents that may help prevent blood clot formation.

Development of Lipoxygenase Inhibitors

Research indicates the use of this compound in synthesising potential lipoxygenase inhibitors. These molecules are investigated for their role in modulating inflammatory pathways.

Organic Synthesis Intermediate

As a versatile building block, 2-(Trifluoromethyl)phenylacetic acid serves as a key intermediate in various organic synthesis projects. Its structure allows for further functionalisation in complex molecule construction.

02 /Properties
Molecular weight204.15
Linear formulaCF3C6H4CH2CO2H
Assay98%
Application2-(Trifluoromethyl)phenylacetic acid has been used in the synthesis of potential antithrombotics1 and lipoxygenase inhibitors2.
Melting point100-102 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-37/39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
3038-48-0
MDL number
MFCD00004327
PubChem substance
24854094
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-(Trifluoromethyl)phenylacetic acid used for?

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2-(Trifluoromethyl)phenylacetic acid is used as a building block in organic synthesis, including the development of potential antithrombotics and lipoxygenase inhibitors.

What are the CAS number and molecular formula for 2-(Trifluoromethyl)phenylacetic acid?

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The CAS number is 3038-48-0 and the molecular formula is CF3C6H4CH2CO2H.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 2-(Trifluoromethyl)phenylacetic acid with a purity of 98%. We do not represent this product as USP, BP, or EP grade.

How should 2-(Trifluoromethyl)phenylacetic acid be handled safely?

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Handling requires appropriate personal protective equipment including a dust mask (N95 type), eyeshields, and gloves. Ensure good ventilation and avoid breathing dust. It is classified as a warning substance with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335).

Does Tech Serve Solutions export 2-(Trifluoromethyl)phenylacetic acid?

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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-(Trifluoromethyl)phenylacetic acid.

How can I request a sample or quote for 2-(Trifluoromethyl)phenylacetic acid?

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Please contact our sales team via the website or by phone to request a sample or obtain a quotation for 2-(Trifluoromethyl)phenylacetic acid.

Need 2-(Trifluoromethyl)phenylacetic acid in a specific grade or volume?