2-(Trifluoromethyl)pyridine-5-boronic acid
2-(Trifluoromethyl)pyridine-5-boronic acid (CAS: 868662-36-6) is a pyridine derivative featuring a boronic acid functional group and a trifluoromethyl substituent. With a molecular weight of 190.92 g/mol and empirical formula C6H5BF3NO2, this organoboron compound serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions for the construction of complex molecules.
Suzuki-Miyaura Cross-Coupling Reactions
This boronic acid is a key reagent in Suzuki-Miyaura coupling, enabling the formation of carbon-carbon bonds by reacting with aryl or vinyl halides. It is widely used in the synthesis of pharmaceuticals and advanced materials.
Heteroaryl Synthesis
It facilitates the introduction of the 2-(trifluoromethyl)pyridin-5-yl moiety into various organic frameworks. This is important for developing novel compounds with potential biological activity or specific material properties.
Medicinal Chemistry Research
The trifluoromethylpyridine core is present in numerous biologically active compounds. This boronic acid serves as a versatile intermediate for structure-activity relationship studies and lead optimization in drug discovery.
| Molecular weight | 190.92 |
|---|---|
| Empirical formula | C6H5BF3NO2 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trifluoromethyl)pyridine-5-boronic acid used for?
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2-(Trifluoromethyl)pyridine-5-boronic acid is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions to create carbon-carbon bonds and introduce the trifluoromethylpyridine fragment into complex molecules for pharmaceutical and materials science applications.
What are the CAS number and chemical formula for 2-(Trifluoromethyl)pyridine-5-boronic acid?
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The CAS number for 2-(Trifluoromethyl)pyridine-5-boronic acid is 868662-36-6, and its chemical formula is C6H5BF3NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Trifluoromethyl)pyridine-5-boronic acid as a research or technical grade material. The specific assay or purity is detailed on the product's Certificate of Analysis. Tech Serve Solutions does not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling considerations for this product?
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According to the WGK classification, this substance is considered hazardous (WGK 3). Handle with appropriate personal protective equipment in a well-ventilated area. Consult the Safety Data Sheet (SDS) for comprehensive safety and handling information.
How is this chemical packed, shipped, and exported?
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This chemical is carefully packed to ensure stability and safety during transit. Tech Serve Solutions is experienced in exporting fine chemicals globally, adhering to all relevant shipping regulations.
How can I request a sample or quote for 2-(Trifluoromethyl)pyridine-5-boronic acid?
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To request a sample or a quote, please use the enquiry form on our website or contact our sales team directly, providing the product name and CAS number (868662-36-6).
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