p-Toluoyl chloride
p-Toluoyl chloride (CAS: 874-60-2) is a valuable organic compound with the linear formula CH3C6H4COCl and a molecular weight of 154.59 g/mol. This acid halide serves as a key intermediate in organic synthesis. It is typically used as a building block for more complex molecules, particularly in the preparation of antigens and other derivatives in chemical research and development settings.
- IUPAC
- 4-Methylbenzoyl chloride
- Synonyms
- 4-Methylbenzoyl chloridep-Tolylcarbonyl chloride
Antigen Preparation
p-Toluoyl chloride has been employed in the synthesis of antigens, such as Tolyl-amido-human serum albumin, for immunological research and diagnostic applications.
Organic Synthesis Intermediate
As a reactive acyl chloride, it functions as a versatile building block for introducing the p-toluoyl group into various organic molecules through acylation reactions.
Laboratory Reagent
It is utilised in research laboratories for custom synthesis projects and the development of novel chemical entities.
| Molecular weight | 154.59 |
|---|---|
| Linear formula | CH3C6H4COCl |
| Assay | 98% |
| Boiling point | 225-227 °C(lit.)95-96 °C/10 mmHg(lit.) |
| Density | 1.169 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.553(lit.) |
| Vapour pressure | 0.55 mmHg (20 °C) |
| Melting point | −4-−2 °C(lit.) |
| Vapour density | 5.33 (vs air) |
| Application | p-Toluoyl chloride was used to prepare antigen, Tolyl-amido-human serum albumin1. |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 82 °C / 179.6 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is p-Toluoyl chloride used for?
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p-Toluoyl chloride is primarily used as an intermediate in organic synthesis, notably for preparing antigens and as a general building block in chemical research.
What is the CAS number and formula for p-Toluoyl chloride?
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The CAS number for p-Toluoyl chloride is 874-60-2, and its linear formula is CH3C6H4COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies p-Toluoyl chloride with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should p-Toluoyl chloride be handled safely?
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p-Toluoyl chloride is a corrosive substance (H314). Handle with appropriate personal protective equipment, including gloves, goggles, a faceshield, and a suitable respirator. Ensure adequate ventilation and avoid contact with skin and eyes.
How is p-Toluoyl chloride packed, shipped, and exported?
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p-Toluoyl chloride is carefully packed according to international shipping regulations (UN 3265, Class 8, PG II) for safe transport and export worldwide by Tech Serve Solutions.
How can I request a sample or quote for p-Toluoyl chloride?
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To request a sample or a quote for p-Toluoyl chloride, please contact our sales team through the Tech Serve Solutions website or your designated account manager.
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