p-Tolyl acetate
p-Tolyl acetate (CAS: 140-39-6; Formula: CH3CO2C6H4CH3; MW: 150.17) is a valuable organic ester utilized in chemical synthesis. It serves as a key building block, particularly in the pharmaceutical sector, and is noted for its role in the total synthesis of complex natural products like (−)-incrustoporin. Tech Serve Solutions supplies this compound with a high purity of 99%, suitable for research and industrial applications.
- IUPAC
- p-Cresyl acetate
- Synonyms
- p-Cresyl acetateAcetic acid, p-tolyl ester
Organic Synthesis
p-Tolyl acetate is employed as a versatile building block in organic synthesis. Its ester functionality and aromatic ring make it suitable for various chemical transformations.
Pharmaceutical Intermediates
This compound has been utilized in multi-step syntheses of biologically active molecules. Notably, it played a role in the total synthesis of the natural product (−)-incrustoporin, highlighting its utility in complex molecule construction.
Research and Development
As a readily available ester, p-Tolyl acetate is a useful reagent in academic and industrial research laboratories for exploring new synthetic routes and developing novel compounds.
| Molecular weight | 150.17 |
|---|---|
| Linear formula | CH3CO2C6H4CH3 |
| Assay | 99% |
| Boiling point | 210-211 °C(lit.) |
| Density | 1.047 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.501(lit.) |
| Application | p-Tolyl acetate has been used in the total synthesis of (−)-incrustoporin1. |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 90 °C / 194 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is p-Tolyl acetate used for?
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p-Tolyl acetate is primarily used as a building block in organic synthesis, including in the total synthesis of natural products like (−)-incrustoporin. It is also utilised in research and development settings.
What are the CAS number and chemical formula for p-Tolyl acetate?
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The CAS number for p-Tolyl acetate is 140-39-6, and its chemical formula is CH3CO2C6H4CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies p-Tolyl acetate with an assay of 99%. This is a technical grade, and TSS does not represent it as USP, BP, or EP.
How should p-Tolyl acetate be handled?
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p-Tolyl acetate is classified as a Warning substance. It is harmful if swallowed, causes skin irritation, serious eye irritation, and may cause respiratory irritation (H302, H315, H319, H335). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (e.g., type ABEK respirator filter), should be used. Ensure good ventilation.
How is p-Tolyl acetate packaged and shipped?
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p-Tolyl acetate is shipped in compliance with regulations, often as NA 1993 / PGIII. Specific packaging details are available upon request, and TSS exports globally.
How can I request a quote or sample?
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To request a quote or a sample of p-Tolyl acetate, please contact our sales team through the website or by phone. Provide your specific requirements and shipping details.
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