p-Tolyl [2-(trimethylsilyl)ethynyl] sulfone
p-Tolyl [2-(trimethylsilyl)ethynyl] sulfone (CAS: 34452-56-7) is a sulfur-containing organic compound with the linear formula (CH₃)₃SiC≡CSO₂C₆H₄CH₃ and a molecular weight of 252.40 g/mol. This specialised building block is valuable in organic synthesis. Its structure, featuring a sulfone group and a silylated alkyne, allows for diverse chemical transformations, making it a useful intermediate for constructing more complex molecules in research and development settings.
- IUPAC
- 1-(p-Toluenesulfonyl)-2-(trimethylsilyl)acetylene,2-(Trimethylsilyl)ethynyl p-tolyl sulfone
- Synonyms
- 1-(p-Toluenesulfonyl)-2-(trimethylsilyl)acetylene2-(Trimethylsilyl)ethynyl p-tolyl sulfone
![p-Tolyl [2-(trimethylsilyl)ethynyl] sulfone ((CH3)3SiC≡CSO2C6H4CH3) — chemical structure, CAS 34452-56-7; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F34452-56-7.png&w=3840&q=75)
Organic Synthesis Intermediate
Utilised as a key building block in the synthesis of complex organic molecules. The presence of the silyl-protected alkyne and the sulfone moiety enables various synthetic pathways for creating novel compounds in medicinal chemistry and materials science.
Research and Development
Employed in academic and industrial research laboratories for the development of new chemical entities and synthetic methodologies. Its unique structural features offer opportunities for exploring novel reactions and generating target molecules.
Sulfone Chemistry
Serves as a valuable reagent in reactions involving sulfone functional groups. It can be used to introduce the p-tolylsulfonyl group or participate in reactions characteristic of activated alkynes.
| Molecular weight | 252.40 |
|---|---|
| Linear formula | (CH3)3SiC≡CSO2C6H4CH3 |
| Assay | ≥97.0% (CHN) |
| Melting point | 80-83 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is p-Tolyl [2-(trimethylsilyl)ethynyl] sulfone used for?
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p-Tolyl [2-(trimethylsilyl)ethynyl] sulfone is primarily used as a building block and intermediate in organic synthesis for the construction of complex molecules, particularly in research and development settings.
What is the CAS number and formula for p-Tolyl [2-(trimethylsilyl)ethynyl] sulfone?
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The CAS number is 34452-56-7 and the linear formula is (CH₃)₃SiC≡CSO₂C₆H₄CH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies p-Tolyl [2-(trimethylsilyl)ethynyl] sulfone with an assay of ≥97.0% (CHN). This product is suitable for research and synthesis purposes and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should p-Tolyl [2-(trimethylsilyl)ethynyl] sulfone be handled?
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Handle p-Tolyl [2-(trimethylsilyl)ethynyl] sulfone with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation. Avoid breathing dust/fume/gas/mist/vapours/spray. Avoid contact with skin and eyes. It may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335).
Is p-Tolyl [2-(trimethylsilyl)ethynyl] sulfone a controlled substance?
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The provided data does not indicate that p-Tolyl [2-(trimethylsilyl)ethynyl] sulfone is a controlled substance.
How is p-Tolyl [2-(trimethylsilyl)ethynyl] sulfone packed, shipped, and exported?
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p-Tolyl [2-(trimethylsilyl)ethynyl] sulfone is carefully packed according to industry standards to ensure safe transit. We offer global shipping and export services for this chemical.
How can I request a sample or quote for p-Tolyl [2-(trimethylsilyl)ethynyl] sulfone?
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To request a sample or a quote, please use the contact form on our website or contact our sales department directly, referencing the product name and CAS number 34452-56-7.
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