p-Tolyl isocyanate
p-Tolyl isocyanate (CAS 622-58-2, CH3C6H4NCO) is a versatile organic compound with a molecular weight of 133.15 g/mol. It is characterised by its isocyanate functional group, making it a valuable intermediate in chemical synthesis. Primarily utilised as a building block, it has been employed in studies involving catalytic processes, such as the reductive carbonylation of nitrobenzene. Available from Tech Serve Solutions with high purity, it serves the needs of research and industrial applications.
- IUPAC
- 4-Methylphenyl isocyanate
- Synonyms
- 4-Methylphenyl isocyanate
Catalysis Research
p-Tolyl isocyanate has been documented in research for its role in studying catalytic systems. For instance, it was used to investigate the catalytic activity of supported Rhodium(I) complexes in the reductive carbonylation of nitrobenzene.
Organic Synthesis Intermediate
As a reactive isocyanate, p-Tolyl isocyanate serves as a crucial building block in organic synthesis. Its structure allows for its incorporation into more complex molecules through various chemical transformations.
Reagent in Chemical Studies
The compound is employed as a reagent in chemical studies, contributing to the development and understanding of synthetic methodologies and reaction mechanisms within organic chemistry.
| Molecular weight | 133.15 |
|---|---|
| Linear formula | CH3C6H4NCO |
| Assay | 99% |
| Boiling point | 70-72 °C/10 mmHg(lit.) |
| Density | 1.056 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.531(lit.) |
| Storage temperature | 2-8°C |
| Application | p-Tolyl isocyanate was used to study the catalytic role of supported Rhodium(I) complex toward the reductive carbonylation of nitrobenzene in DMF medium1. |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 66 °C / 150.8 °F |
| Transport (UN / ADR) | UN 3334 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38-42 |
| Safety statements (S) | 23-26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is p-Tolyl isocyanate used for?
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p-Tolyl isocyanate is used as a building block in organic synthesis and has been employed in research to study catalytic processes, such as the reductive carbonylation of nitrobenzene.
What are the CAS number and formula for p-Tolyl isocyanate?
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The CAS number for p-Tolyl isocyanate is 622-58-2, and its chemical formula is CH3C6H4NCO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies p-Tolyl isocyanate with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should p-Tolyl isocyanate be handled safely?
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p-Tolyl isocyanate is a Danger substance, harmful if swallowed, in contact with skin, or if inhaled (H302 + H312 + H332). It causes skin irritation (H315), serious eye irritation (H319), and may cause allergy or asthma symptoms or breathing difficulties if inhaled (H334), and respiratory irritation (H335). Always use appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a suitable respirator, and handle in a well-ventilated area.
How is p-Tolyl isocyanate packed, shipped, and exported?
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p-Tolyl isocyanate is packed and shipped according to international regulations for hazardous materials. As a global supplier, Tech Serve Solutions handles all necessary export documentation and compliance.
How can I request a sample or quote for p-Tolyl isocyanate?
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To request a sample or a quote for p-Tolyl isocyanate, please contact our sales team through the details provided on the Tech Serve Solutions website.
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