p-Tolylacetic acid
p-Tolylacetic acid (CAS: 622-47-9), with the molecular formula CH3C6H4CH2CO2H and a molar mass of 150.17 g/mol, is a carboxylic acid derivative. It serves as a valuable building block in organic synthesis. Its structure lends itself to various chemical transformations, making it a useful intermediate for the preparation of more complex organic molecules in research and industrial applications.
- IUPAC
- 4-Methylphenylacetic acid
- Synonyms
- 4-Methylphenylacetic acid(4-Methylphenyl)acetic acid2-(p-Tolyl)acetic acid

Organic Synthesis Intermediate
p-Tolylacetic acid is frequently employed as a starting material or intermediate in the synthesis of complex organic compounds. Its reactive carboxylic acid group and aromatic ring allow for diverse chemical modifications.
Pharmaceutical Research
This compound can be utilised in the development of new pharmaceutical agents. Its structural features may be incorporated into drug candidates during the research and development phase.
Material Science
Potential applications exist in material science, where p-tolylacetic acid derivatives could be investigated for their properties in polymers or functional materials.
| Molecular weight | 150.17 |
|---|---|
| Linear formula | CH3C6H4CH2CO2H |
| Assay | 99% |
| Grade | ReagentPlus® |
| Boiling point | 265-267 °C(lit.) |
| Melting point | 88-92 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is p-Tolylacetic acid used for?
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p-Tolylacetic acid is primarily used as a building block and intermediate in organic synthesis, with potential applications in pharmaceutical research and material science.
What is the CAS number and chemical formula for p-Tolylacetic acid?
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The CAS number is 622-47-9 and the chemical formula is CH3C6H4CH2CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies p-Tolylacetic acid at a ReagentPlus® grade with an assay of 99%. This product is not represented as USP, BP, or EP grade.
What are the safety and handling precautions for p-Tolylacetic acid?
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p-Tolylacetic acid is a warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, should be worn. Handle in a well-ventilated area.
How is p-Tolylacetic acid packed, shipped, and exported?
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Tech Serve Solutions expertly packs, handles, and exports chemicals globally, adhering to all necessary regulations for safe and compliant transit.
How can I request a quote or sample for p-Tolylacetic acid?
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To request a quote or sample, please contact our sales team via the website or direct inquiry, providing your specific requirements.
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