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p-Toluidine

CAS 106-49-0CH3C6H4NH2Chemical Synthesis

p-Toluidine (CAS: 106-49-0), with the molecular formula CH3C6H4NH2 and a molar mass of 107.15 g/mol, is an aromatic amine. This compound serves as a vital intermediate and building block in various chemical synthesis pathways. Its applications span the production of dyes, agricultural chemicals, and pharmaceuticals, underscoring its importance in organic chemistry and industrial processes. Tech Serve Solutions supplies high-purity p-Toluidine for research and manufacturing.

IUPAC
4-Aminotoluene,4-Methylaniline
Synonyms
4-Aminotoluene4-Methylanilinep-Aminotoluenep-MethylanilineBenzeneamine, 4-methyl-
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p-Toluidine (CH3C6H4NH2) — chemical structure, CAS 106-49-0; Chemistry, fine chemical supplied by Tech Serve Solutions
AminesBuilding BlocksChemical SynthesisNitrogen Compounds
01 /Applications

Dye and Pigment Synthesis

p-Toluidine is a key precursor in the manufacture of azo dyes and pigments, contributing to a wide spectrum of colours used in textiles and printing industries.

Agrochemical Intermediates

It functions as a building block in the synthesis of certain pesticides and herbicides, playing a role in crop protection chemicals.

Pharmaceutical Intermediates

The compound is utilized in the multi-step synthesis of various pharmaceutical agents and active ingredients.

Organic Synthesis Reagent

As a versatile aromatic amine, p-Toluidine is employed in numerous organic reactions for creating complex molecules.

02 /Properties
Molecular weight107.15
Linear formulaCH3C6H4NH2
Assay99.6%
Boiling point200 °C(lit.)
Density0.973 g/mL at 25 °C(lit.)
Solubilitywater: soluble135 part(lit.)acetone: freely soluble(lit.)alcohol: freely soluble(lit.)carbon disulfide: freely soluble(lit.)diethyl ether: freely soluble(lit.)methanol: freely soluble(lit.)oil: freely soluble(lit.)
Vapour pressure0.26 mmHg (25 °C)0.66 mmHg (38 °C)
Melting point41-46 °C(lit.)
Vapour density3.9 (vs air)
Autoignition temp899 °F
03 /Safety & handling
GHS hazard pictogram: Toxic (GHS06)
Toxic
GHS hazard pictogram: Health hazard (GHS08)
Health hazard
GHS hazard pictogram: Environmental hazard (GHS09)
Environmental hazard
Danger

Hazard statements

  • H301Toxic if swallowed
  • H311Toxic in contact with skin
  • H317May cause an allergic skin reaction
  • H319Causes serious eye irritation
  • H331Toxic if inhaled
  • H351Suspected of causing cancer
  • H400Very toxic to aquatic life

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P273Avoid release to the environment
  • P280Wear protective gloves, clothing and eye/face protection
  • P301IF SWALLOWED
  • P305IF IN EYES
  • P311Call a POISON CENTER or doctor
Protective equipmentEyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Flash point87 °C / 188.6 °F
Transport (UN / ADR)UN 3451 6.1 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)T,N
Risk statements (R)23/24/25-36-40-43-50
Safety statements (S)28-36/37-45-61

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
106-49-0
MDL number
MFCD00007906
PubChem substance
24869813
Beilstein registry
471281
05 /Additional specifications
Expl Lim6.6 %
06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is p-Toluidine used for?

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p-Toluidine is primarily used as an intermediate in the synthesis of dyes, pigments, agrochemicals, and pharmaceuticals, as well as a general reagent in organic synthesis.

What is the CAS number and chemical formula for p-Toluidine?

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The CAS number for p-Toluidine is 106-49-0, and its chemical formula is CH3C6H4NH2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies p-Toluidine with an assay of 99.6%. This is a technical/research grade, and TSS does not represent it as USP, BP, or EP grade.

How should p-Toluidine be handled safely?

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p-Toluidine is a toxic and sensitizing substance. Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection (NIOSH N100 or equivalent), in a well-ventilated area. Avoid skin and eye contact, and inhalation of vapours.

How is p-Toluidine packed, shipped, and exported?

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p-Toluidine is securely packed according to international shipping regulations for hazardous materials, and TSS exports globally.

How can I request a sample or quote for p-Toluidine?

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To request a sample or a quote for p-Toluidine, please contact our sales department through the website or by phone.

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