p-Toluenesulfonyl isocyanate
p-Toluenesulfonyl isocyanate (CAS 4083-64-1), molecular formula CH3C6H4SO2NCO, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.
- IUPAC
- Tosyl isocyanate
| Molecular weight | 197.21 |
|---|---|
| Linear formula | CH3C6H4SO2NCO |
| Assay | 96% |
| Boiling point | 144 °C/10 mmHg(lit.)275-278 °C(lit.) |
| Density | 1.291 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.534(lit.) |
| Vapour pressure | 1 mmHg (100 °C) |
| Application | p-Toluenesulfonyl isocyanate has been used as :• derivatization reagent in determination of 3-α-hydroxy tibolone in human plasma by LC-MS/MS1 • derivatization reagent in simultaneous quantitative analysis of diethylene glycol and propylene glycol in pharmaceutical products by HPLC2 • as reagent in the preparation of acetylated syn-1,2-diols3, oxazolidin-2-ones4, 2,3-diamino acids5 and N-tosylcarbonamides6 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P342
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 145 °C / 293 °F |
| Transport (UN / ADR) | UN 2206 6.1/PG 3 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 14-36/37/38-42 |
| Safety statements (S) | 26-28-30 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is p-Toluenesulfonyl isocyanate?
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p-Toluenesulfonyl isocyanate (CAS 4083-64-1), molecular formula CH3C6H4SO2NCO, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to USP, BP and EP standards.
What grades of p-Toluenesulfonyl isocyanate does Tech Serve Solutions supply?
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Tech Serve Solutions supplies p-Toluenesulfonyl isocyanate in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.
What is the CAS number and molecular formula of p-Toluenesulfonyl isocyanate?
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p-Toluenesulfonyl isocyanate has CAS number 4083-64-1 and molecular formula CH3C6H4SO2NCO. Full specifications appear in the table above and in the Certificate of Analysis.
What is the typical minimum order quantity and lead time for p-Toluenesulfonyl isocyanate?
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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.
Do you provide a Certificate of Analysis (CoA) with each shipment?
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Yes. Every batch of p-Toluenesulfonyl isocyanate ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.
How should p-Toluenesulfonyl isocyanate be stored?
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Store p-Toluenesulfonyl isocyanate in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.
What is p-Toluenesulfonyl isocyanate used for?
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p-Toluenesulfonyl isocyanate is used in chemical synthesis applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.
How do I request a quote for p-Toluenesulfonyl isocyanate?
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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.
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