2-(Trifluoromethyl)quinoline
2-(Trifluoromethyl)quinoline (CAS: 347-42-2), with the molecular formula C10H6F3N and a molecular weight of 197.16 g/mol, is a heterocyclic organic compound. It serves as a valuable building block in chemical synthesis, particularly within the realm of developing novel pharmaceutical intermediates and complex organic molecules. Its trifluoromethyl group offers unique electronic and steric properties for molecular design.

Chemical Synthesis Intermediate
2-(Trifluoromethyl)quinoline is employed as a key intermediate in the synthesis of more complex organic compounds. Its structure is often incorporated into molecules for research and development in areas such as medicinal chemistry and materials science.
Pharmaceutical Research
This compound can act as a building block for the discovery and development of new pharmaceutical agents. The quinoline scaffold and the trifluoromethyl substituent are recognised motifs in drug design, potentially influencing biological activity and pharmacokinetic properties.
Heterocyclic Chemistry
As a substituted quinoline, it is a useful reagent in heterocyclic chemistry. Researchers utilise it to explore novel reaction pathways and to construct diverse molecular architectures featuring the quinoline core.
| Molecular weight | 197.16 |
|---|---|
| Empirical formula | C10H6F3N |
| Assay | 97% |
| Melting point | 58-62 °C |

Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Trifluoromethyl)quinoline used for?
+
2-(Trifluoromethyl)quinoline is primarily used as a building block in chemical synthesis, particularly for the development of pharmaceutical intermediates and novel organic molecules in research settings.
What are the CAS number and molecular formula for 2-(Trifluoromethyl)quinoline?
+
The CAS number for 2-(Trifluoromethyl)quinoline is 347-42-2, and its molecular formula is C10H6F3N.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-(Trifluoromethyl)quinoline with an assay of 97%. This product is suitable for research and chemical synthesis purposes; TSS does not represent it as USP, BP, or EP grade.
How should 2-(Trifluoromethyl)quinoline be handled safely?
+
2-(Trifluoromethyl)quinoline is classified as dangerous. It is harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation. Always handle with appropriate personal protective equipment (PPE) in a well-ventilated area, following safety data sheet (SDS) guidelines. Avoid inhalation, ingestion, and contact with skin and eyes.
How is 2-(Trifluoromethyl)quinoline packed, shipped, and exported?
+
Tech Serve Solutions professionally packs and ships 2-(Trifluoromethyl)quinoline according to international regulations for hazardous materials. As a global supplier, we expertly handle export documentation and logistics to ensure safe and compliant delivery worldwide.
How can I request a sample or quote for 2-(Trifluoromethyl)quinoline?
+
To request a sample or a quote for 2-(Trifluoromethyl)quinoline, please contact our sales team through the website or by phone. Provide your contact details and the quantity required, and we will respond promptly.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis