Boc-Arg-OH
Boc-Arg-OH (CAS: 13726-76-6), also known as Nα-(tert-Butoxycarbonyl)-L-arginine, is a protected amino acid derivative with a molecular weight of 274.32 g/mol. It is primarily utilised in peptide synthesis and chemical biology research. This compound is essential for building complex peptide chains where specific protection of the arginine side chain is required, enabling controlled synthesis of biologically relevant molecules and therapeutic peptides.
- IUPAC
- Nα-(tert-Butoxycarbonyl)-L-arginine,Nα-Boc-L-arginine
- Synonyms
- Nα-(tert-Butoxycarbonyl)-L-arginineNα-Boc-L-arginine
Peptide Synthesis
Boc-Arg-OH is a key building block in solid-phase and solution-phase peptide synthesis. The tert-butoxycarbonyl (Boc) protecting group on the alpha-amino group allows for controlled coupling reactions in the stepwise assembly of peptide sequences, particularly when the guanidino group of arginine needs to remain free or is protected separately.
Chemical Biology Research
In chemical biology, Boc-Arg-OH is used to synthesise modified peptides or peptidomimetics. These molecules can serve as probes to study biological pathways, protein-protein interactions, or as starting points for drug discovery efforts.
Pharmaceutical Intermediate
As a protected amino acid, Boc-Arg-OH serves as an intermediate in the synthesis of pharmacologically active peptides or complex organic molecules. Its defined structure and protecting group facilitate its incorporation into multi-step synthetic routes for potential therapeutic agents.
| Molecular weight | 274.32 |
|---|---|
| Linear formula | HN=C(NH2)NH(CH2)3CH(COOH)NHC(O)OC(CH3)3 |
| Optical activity | [α]20/D −6.5°, c = 1 in acetic acid |
| Impurities tested | 5-10% n-butanol |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Arg-OH used for?
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Boc-Arg-OH is primarily used as a building block in peptide synthesis and in chemical biology research for constructing complex peptides and peptidomimetics.
What is the CAS number and linear formula for Boc-Arg-OH?
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The CAS number for Boc-Arg-OH is 13726-76-6. The linear formula is HN=C(NH2)NH(CH2)3CH(COOH)NHC(O)OC(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Arg-OH with an impurity profile of 5-10% n-butanol. We do not represent this product as USP, BP, or EP grade.
What are the safety precautions for handling Boc-Arg-OH?
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When handling Boc-Arg-OH, wear safety glasses, gloves, and a type N95 (US) or P1 (EN143) respirator filter. The flash point is 113 °C (235.4 °F), indicating it is combustible.
How is Boc-Arg-OH packed and exported?
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Tech Serve Solutions reliably packs and exports Boc-Arg-OH globally, adhering to all necessary regulations for chemical handling and transportation.
How can I request a sample or quote for Boc-Arg-OH?
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To request a sample or a quote for Boc-Arg-OH, please contact our sales department via the website or direct email.
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