Boc-Arg(Tos)-OH
Nα-Boc-Nω-tosyl-L-arginine (CAS: 13836-37-8), a protected amino acid derivative with formula C18H28N4O6S and a molecular weight of 428.50 g/mol, is primarily employed in peptide synthesis. This compound features a tert-butyloxycarbonyl (Boc) protecting group on the alpha-amino group and a tosyl group on the side-chain guanidino moiety. It serves as a crucial building block for constructing complex peptides, particularly those requiring the incorporation of arginine with a protected side chain.
- IUPAC
- Nα-Boc-Nω-tosyl-L-arginine
Peptide Synthesis
Nα-Boc-Nω-tosyl-L-arginine is extensively used as a protected amino acid in solid-phase and solution-phase peptide synthesis. The Boc and tosyl groups facilitate controlled coupling reactions, preventing unwanted side reactions during peptide chain elongation.
Chemical Synthesis
This derivative acts as a valuable intermediate in the synthesis of peptides and peptidomimetics. Its defined protecting groups allow for selective deprotection and further functionalization in multi-step organic synthesis pathways.
Biochemical Research
As a protected form of arginine, it is utilized in biochemical studies and the development of modified amino acids for research purposes. Its incorporation can modulate peptide properties and functions.
| Molecular weight | 428.50 |
|---|---|
| Empirical formula | C18H28N4O6S |
| Optical activity | [α]20/D −3.5±0.5°, c = 4% in DMF |
| Impurities tested | ~2% water |
| Melting point | ~90 °C (dec.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nα-Boc-Nω-tosyl-L-arginine used for?
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Nα-Boc-Nω-tosyl-L-arginine is primarily used as a protected amino acid building block in peptide synthesis and other chemical synthesis applications.
What are the CAS number and formula for Nα-Boc-Nω-tosyl-L-arginine?
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The CAS number is 13836-37-8, and the empirical formula is C18H28N4O6S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with approximately 2% water content. We do not represent this product as USP, BP, or EP grade; it is intended for research and chemical synthesis use.
How should Nα-Boc-Nω-tosyl-L-arginine be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Avoid contact with eyes and skin. Refer to the Safety Data Sheet for comprehensive handling information.
Is this product a controlled substance?
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Based on the provided data, there is no indication that Nα-Boc-Nω-tosyl-L-arginine is a controlled substance.
How is Nα-Boc-Nω-tosyl-L-arginine shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and this product can be packed and shipped according to international regulations for chemical export.
How can I request a sample or quote for Nα-Boc-Nω-tosyl-L-arginine?
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Please contact our sales team via the website or direct inquiry channels to request a sample or obtain a quotation for Nα-Boc-Nω-tosyl-L-arginine.
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