Boc-Arg(Pbf)-OH
Boc-Arg(Pbf)-OH (CAS 200124-22-7), with the molecular formula C24H38N4O7S and a molecular weight of 526.65, is a protected amino acid derivative. It is primarily utilized in peptide synthesis and related chemical research fields. This compound serves as a crucial building block for incorporating the modified arginine residue into peptide chains, facilitating the study of complex biomolecules and the development of novel therapeutics.
- IUPAC
- Nα-Boc-Nω-(2,2,4,6,7-pentamethyl-dihydrobenzofuran-5-sulfonyl)-L-arginine,Nα-Boc-Nω-Pbf-L-arginine
- Synonyms
- Nα-Boc-Nω-(2,2,4,6,7-pentamethyl-dihydrobenzofuran-5-sulfonyl)-L-arginine, Nα-Boc-Nω-Pbf-L-arginine
Peptide Synthesis
Boc-Arg(Pbf)-OH is extensively used as a protected amino acid in solid-phase and solution-phase peptide synthesis. The Boc (tert-butyloxycarbonyl) group provides temporary protection for the alpha-amino group, while the Pbf (2,2,4,6,7-pentamethyl-dihydrobenzofuran-5-sulfonyl) group protects the guanidino side chain of arginine.
Chemical Biology Research
This derivative enables researchers to construct peptides with specific arginine modifications. Such modified peptides are instrumental in studying protein-ligand interactions, enzyme mechanisms, and cellular signalling pathways.
Organic Synthesis
As a versatile chemical intermediate, Boc-Arg(Pbf)-OH finds application in complex organic synthesis projects beyond just peptide chains, where a protected arginine moiety is required.
| Molecular weight | 526.65 |
|---|---|
| Empirical formula | C24H38N4O7S |
| Assay | ≥98.0% (TLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Boc-Arg(Pbf)-OH used for?
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Boc-Arg(Pbf)-OH is primarily used in peptide synthesis as a protected building block for incorporating modified arginine into peptide sequences, and in chemical biology and organic synthesis research.
What is the CAS number and molecular formula for Boc-Arg(Pbf)-OH?
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The CAS number for Boc-Arg(Pbf)-OH is 200124-22-7, and its molecular formula is C24H38N4O7S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Boc-Arg(Pbf)-OH with an assay of ≥98.0% (TLC). We do not represent this product as USP, BP, or EP grade.
How should Boc-Arg(Pbf)-OH be handled safely?
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When handling Boc-Arg(Pbf)-OH, it is essential to wear eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. The compound is classified under WGK 2 (Germany).
Does Tech Serve Solutions export Boc-Arg(Pbf)-OH?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Boc-Arg(Pbf)-OH.
How can I request a quote or sample for Boc-Arg(Pbf)-OH?
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To request a quote or sample for Boc-Arg(Pbf)-OH, please contact our sales team through the website or by phone.
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