Boc-Asn-OH

CAS 7536-55-2NH2COCH2CH(COOH)NHC(O)OC(CH3)3Chemical Synthesis

Boc-Asn-OH (CAS 7536-55-2), or Nα-(tert-Butoxycarbonyl)-L-asparagine, is a protected amino acid derivative with a molecular weight of 232.23 g/mol. This white crystalline solid is an essential building block in peptide synthesis. Its tert-butoxycarbonyl (Boc) protecting group offers selective deprotection under mild acidic conditions, making it valuable in constructing complex peptide sequences for research and development in chemical biology and pharmaceuticals.

IUPAC: Nα-(tert-Butoxycarbonyl)-L-asparagine,Boc-L-asparagine
Synonyms: N-alpha-(tert-Butoxycarbonyl)-L-asparagineBoc-L-asparagine

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Boc-Asn-OH (NH2COCH2CH(COOH)NHC(O)OC(CH3)3) — chemical structure, CAS 7536-55-2; Chemistry, fine chemical supplied by Tech Serve Solutions

Amino Acid DerivativesAsparagineChemical BiologyChemical SynthesisPeptide Chemistry

01 /Applications

Peptide Synthesis

Boc-Asn-OH serves as a crucial protected amino acid in solid-phase and solution-phase peptide synthesis. The Boc group facilitates controlled coupling reactions, enabling the sequential assembly of peptides and peptidomimetics.

Chemical Biology Research

This compound is utilized in the synthesis of peptides and modified peptides for studying biological processes, protein function, and drug discovery. It allows for the introduction of asparagine residues into specific sequences with high fidelity.

Pharmaceutical Intermediate

As a key intermediate, Boc-Asn-OH is employed in the synthetic routes for various active pharmaceutical ingredients (APIs) and therapeutic peptides. Its controlled reactivity is vital for multistep syntheses.

Organic Synthesis

Beyond peptide chemistry, Boc-Asn-OH can be used in general organic synthesis as a chiral building block for the preparation of complex molecules requiring an asparagine moiety or its protected form.

02 /Properties

Molecular weight	232.23
Linear formula	NH2COCH2CH(COOH)NHC(O)OC(CH3)3
Assay	≥98.5% (T)
Optical activity	[α]20/D −7.8±0.5°, c = 2% in DMF
Melting point	175 °C (dec.)(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3
Ignition residue	≤0.2%

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

7536-55-2

MDL number

MFCD00038152

Beilstein registry

1977963

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Boc-Asn-OH used for?

Boc-Asn-OH is primarily used as a protected amino acid in peptide synthesis, for research in chemical biology, and as an intermediate in the synthesis of pharmaceuticals and complex organic molecules.

What is the CAS number and formula for Boc-Asn-OH?

The CAS number is 7536-55-2. The linear formula is NH₂COCH₂CH(COOH)NHC(O)OC(CH₃)₃.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Boc-Asn-OH with an assay of ≥98.5% (T). We do not represent this product as USP, BP, or EP grade.

How should Boc-Asn-OH be handled safely?

Handle Boc-Asn-OH with appropriate personal protective equipment, including eyeshields and gloves. Ensure adequate ventilation and use a P1 (EN143) or N95 (US) respirator if dust is generated. Avoid contact with skin and eyes.

Does Boc-Asn-OH have any specific shipping or packaging requirements?

While specific requirements vary, this chemical is typically packaged to ensure stability during transport. TSS exports globally, adhering to all relevant shipping regulations.