1H,1H,2H-Perfluoro-1-octene
1H,1H,2H-Perfluoro-1-octene (CAS: 25291-17-2) is a fluorinated alkene with the linear formula CF3(CF2)5CH=CH2 and a molecular weight of 346.09 g/mol. This compound is primarily utilised in chemical synthesis, particularly within the specialised fields of fluorous synthesis and as a precursor for Rf-tagged building blocks. Its unique perfluorinated structure makes it valuable for introducing fluorinated segments into organic molecules, enabling tailored properties for advanced material science and chemical research.
- IUPAC
- 1H,1H,2H-Perfluoro-1-octene,3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluoro-1-octene
- Synonyms
- 25291-17-2CF3(CF2)5CH=CH23,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluoro-1-octene

Fluorous Synthesis
1H,1H,2H-Perfluoro-1-octene serves as a key building block in fluorous synthesis, a technique that leverages the distinct solubility properties of highly fluorinated compounds for separation and purification.
Rf-Tagged Building Blocks
It is employed in the preparation of Rf-tagged molecules, which are useful for chromatographic separation, solid-phase synthesis, and as tracers in various chemical and biological studies.
Specialty Chemical Synthesis
The compound is used as a reactant in the synthesis of specialised fluorinated organic compounds, contributing unique properties like hydrophobicity and thermal stability.
| Molecular weight | 346.09 |
|---|---|
| Linear formula | CF3(CF2)5CH=CH2 |
| Assay | 99% |
| Boiling point | 102-104 °C(lit.) |
| Density | 1.52 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.295(lit.) |


Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 20 °C / 68 °F |
| Transport (UN / ADR) | UN 1993BF 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1H,1H,2H-Perfluoro-1-octene used for?
+
1H,1H,2H-Perfluoro-1-octene is used in chemical synthesis, particularly for fluorous synthesis and as a precursor for Rf-tagged building blocks and other specialty fluorinated compounds.
What are the CAS number and chemical formula for 1H,1H,2H-Perfluoro-1-octene?
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The CAS number is 25291-17-2 and the linear formula is CF3(CF2)5CH=CH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1H,1H,2H-Perfluoro-1-octene with an assay of 99%. This product is not intended for pharmaceutical, nutraceutical, or food use, and TSS does not represent it as USP, BP, or EP grade.
How should 1H,1H,2H-Perfluoro-1-octene be handled safely?
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This compound is flammable and can cause skin irritation, serious eye irritation, and respiratory irritation. Handle with appropriate personal protective equipment including eyeshields, gloves, and a suitable respirator. Ensure adequate ventilation and keep away from heat and ignition sources.
How is 1H,1H,2H-Perfluoro-1-octene packed and shipped?
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1H,1H,2H-Perfluoro-1-octene is shipped according to regulations for flammable liquids, such as UN 1993. Specific packaging details are available upon request for export orders.
How can I request a sample or quote for 1H,1H,2H-Perfluoro-1-octene?
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To request a sample or quote, please contact the TSS sales team via our website or direct email, providing your specific requirements and shipping details.
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