4-Bromo-3-(trifluoromethyl)benzenesulfonyl chloride
Tech Serve Solutions supplies 4-Bromo-3-(trifluoromethyl)benzenesulfonyl chloride (CAS 351003-47-9), a key organic building block with the molecular formula BrC6H3(CF3)SO2Cl and a molecular weight of 323.51 g/mol. This compound serves as a versatile intermediate in organic synthesis, particularly valuable for introducing the 4-bromo-3-(trifluoromethyl)benzenesulfonyl moiety into target molecules. Its reactivity makes it suitable for various coupling reactions and derivatisations in research and development settings.

Organic Synthesis Intermediate
This sulfonyl chloride is a valuable reagent for the synthesis of complex organic molecules. It can be used in the preparation of sulfonamides, sulfonate esters, and other sulfur-containing compounds.
Pharmaceutical Research
As a building block, it aids in the construction of novel molecular scaffolds for potential pharmaceutical agents. Its unique substitution pattern can influence the biological activity of derived compounds.
Agrochemical Development
The trifluoromethyl and bromo substituents can impart specific properties desirable in agrochemical compounds, such as enhanced efficacy or metabolic stability. This makes it a useful intermediate in this field.
| Molecular weight | 323.51 |
|---|---|
| Linear formula | BrC6H3(CF3)SO2Cl |
| Assay | 97% |
| Density | 1.833 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5360(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromo-3-(trifluoromethyl)benzenesulfonyl chloride used for?
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It is primarily used as an intermediate and building block in organic synthesis, particularly in pharmaceutical and agrochemical research and development.
What are the CAS number and chemical formula for this compound?
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The CAS number is 351003-47-9 and the chemical formula is BrC6H3(CF3)SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with a minimum assay of 97%. We do not represent it as USP, BP, EP, or pharmacopoeia grade unless explicitly stated.
How should 4-Bromo-3-(trifluoromethyl)benzenesulfonyl chloride be handled safely?
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This compound is classified as corrosive (H314) and requires appropriate personal protective equipment including face shields, goggles, and chemical-resistant gloves. Handling should occur in a well-ventilated area or fume hood.
Is this chemical shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-Bromo-3-(trifluoromethyl)benzenesulfonyl chloride.
How can I request a quote or sample?
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Please contact our sales department via the website or directly by phone to request a quotation or a sample of 4-Bromo-3-(trifluoromethyl)benzenesulfonyl chloride.
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