1H-1,2,4-Triazole-1-carboxamidine hydrochloride
1H-1,2,4-Triazole-1-carboxamidine hydrochloride (CAS 19503-26-5) is a chemical compound with the molecular formula C3H5N5 · HCl and a molecular weight of 147.57 g/mol. It serves as a valuable guanylating agent, facilitating reactions under mild conditions using water or alcohols as solvents. Its applications are primarily found in chemical synthesis, particularly in peptide chemistry and guanidine protection/guanidinylation processes.
- IUPAC
- 1-Amidino-1H-1,2,4-triazole hydrochloride
- Synonyms
- 19503-26-5C3H5N5 · HCl1-Amidino-1H-1,2,4-triazole hydrochloride
Guanylating Agent
This compound functions effectively as a guanylating agent. It enables the introduction of a guanidine group in organic synthesis, often employing water and alcohols as reaction media.
Peptide Chemistry
In peptide synthesis, it can be utilised for guanidine protection or guanidinylation, allowing for controlled modification of amino acid residues.
Chemical Synthesis
It is a useful reagent in general chemical synthesis, offering mild reaction conditions and often yielding good results in various synthetic pathways.
Chemical Biology
Its properties make it a relevant compound for applications within chemical biology research, aiding in the study of biological molecules and processes.
| Molecular weight | 147.57 |
|---|---|
| Empirical formula | C3H5N5 · HCl |
| Assay | ≥98.0% (AT) |
| Application | Guanylating agent using water and alcohols as solvents, high yields, mild conditions; |
| Melting point | 215-220 °C |
Hazard statements
- H301Toxic if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1H-1,2,4-Triazole-1-carboxamidine hydrochloride used for?
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1H-1,2,4-Triazole-1-carboxamidine hydrochloride is primarily used as a guanylating agent in chemical synthesis, including peptide chemistry and guanidine protection/guanidinylation, often under mild conditions with water or alcohols as solvents.
What is the CAS number and formula for 1H-1,2,4-Triazole-1-carboxamidine hydrochloride?
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The CAS number for 1H-1,2,4-Triazole-1-carboxamidine hydrochloride is 19503-26-5. Its empirical formula is C3H5N5 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1H-1,2,4-Triazole-1-carboxamidine hydrochloride with an assay of ≥98.0% (AT). We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.
How should 1H-1,2,4-Triazole-1-carboxamidine hydrochloride be handled?
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This compound is classified as toxic if swallowed (H301) and causes serious eye irritation (H319). Handle with appropriate personal protective equipment, including a dust mask (type N95 recommended), eyeshields, faceshields, and gloves. Ensure adequate ventilation.
Is 1H-1,2,4-Triazole-1-carboxamidine hydrochloride a controlled substance?
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The provided data does not indicate that 1H-1,2,4-Triazole-1-carboxamidine hydrochloride is a controlled substance.
How is 1H-1,2,4-Triazole-1-carboxamidine hydrochloride typically packed and shipped?
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Products are packed according to industry standards to ensure safe transit. As a global supplier, Tech Serve Solutions exports chemicals worldwide, adhering to all relevant shipping regulations.
How can I request a sample or quote for 1H-1,2,4-Triazole-1-carboxamidine hydrochloride?
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To request a sample or a quote, please contact our sales team through the website or by calling our office. Please specify the product name and CAS number (19503-26-5) in your inquiry.
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