TES

CAS 7365-44-8C6H15NO6SBiochemicals & Reagents

2-[(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]ethanesulfonic acid (CAS 7365-44-8), commonly known as TES, is a zwitterionic organic chemical compound with the formula C6H15NO6S and a molecular weight of 229.25 g/mol. It functions as a biological buffer, maintaining stable pH in the range of 6.8 to 8.2. Its suitability for cell culture and low endotoxin levels make it valuable in biochemical research and related applications.

IUPAC: 2-[(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]ethanesulfonic acid,N-[Tris(hydroxymethyl)methyl]-2-aminoethanesulfonic acid,TES free acid
Synonyms: 2-\(2-Hydroxy-1,1-bis\(hydroxymethyl\)ethyl\)amino\-ethanesulfonic acidN-\[Tris\(hydroxymethyl\)methyl\]\-2-aminoethanesulfonic acidTES free acid

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TES (C6H15NO6S) — chemical structure, CAS 7365-44-8; Life Science, fine chemical supplied by Tech Serve Solutions

BioXtra BuffersBiochemicals and ReagentsBiological BuffersBuffers A to ZGood’s Buffers

01 /Applications

Biological Buffering Agent

TES is widely employed as a buffer in biological and biochemical research due to its pKa of approximately 7.4-7.5 and its ability to maintain stable pH in the physiological range of 6.8 to 8.2. This stability is crucial for enzyme assays, protein purification, and cell culture media.

Cell Culture Applications

With suitability for cell culture tested and low endotoxin and microbial counts, TES is an excellent choice for maintaining the pH of cell culture media. It supports optimal cellular growth and function without interfering with biological processes.

Biochemical Reagent

As a zwitterionic compound, TES can be used in various biochemical procedures where precise pH control is required. Its chemical properties allow it to be compatible with many biological molecules and experimental conditions.

02 /Properties

Molecular weight	229.25
Empirical formula	C6H15NO6S
Assay	≥99% (titration)
Impurities tested	endotoxin and total aerobic microbial count, tested
Suitability	cell culture tested
Melting point	~225 °C (dec.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	1
Cation traces	heavy metals (as Pb): ≤5 ppm

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

7365-44-8

MDL number

MFCD00007532

PubChem substance

24900386

Beilstein registry

1957061

05 /Additional specifications

Useful Ph Range	6.8 - 8.2

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is TES used for?

TES is primarily used as a biological buffer in research and cell culture applications, maintaining stable pH between 6.8 and 8.2.

What is the CAS number and formula for TES?

The CAS number for TES is 7365-44-8, and its empirical formula is C6H15NO6S.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies TES with an assay of ≥99% (titration) and suitability for cell culture. It is tested for endotoxins and total aerobic microbial count. This product is not supplied as USP, BP, or EP grade.

How should TES be handled safely?

When handling TES, use appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Avoid contact with eyes and skin. Refer to the Safety Data Sheet for comprehensive handling information.