TAPSO
TAPSO (CAS: 68399-81-5, C7H17NO7S) is a zwitterionic organic chemical compound with a molecular weight of 259.28 g/mol. It belongs to the Good’s buffers group, exhibiting excellent buffering capacity within the physiological pH range. TAPSO is commonly employed in biological and biochemical research, particularly in diagnostic assay manufacturing, owing to its high purity and low UV absorbance.
- IUPAC
- 2-Hydroxy-3-[tris(hydroxymethyl)methylamino]-1-propanesulfonic acid,N-[Tris(hydroxymethyl)methyl]-3-amino-2-hydroxypropanesulfonic acid
- Synonyms
- 2-Hydroxy-3-[tris(hydroxymethyl)methylamino]-1-propanesulfonic acidN-[Tris(hydroxymethyl)methyl]-3-amino-2-hydroxypropanesulfonic acid

Biochemical Research
TAPSO serves as a reliable buffer in various biochemical assays and experiments, maintaining stable pH conditions crucial for enzyme activity and biological sample integrity.
Diagnostic Assay Manufacturing
Its specific properties make it suitable for the development and production of diagnostic kits and reagents, ensuring consistent performance and reliable results.
Protein Chemistry
This buffer is utilized in protein purification and analysis, where maintaining a specific pH is essential to preserve protein structure and function.
| Molecular weight | 259.28 |
|---|---|
| Empirical formula | C7H17NO7S |
| Assay | ≥99% (titration) |
| Solubility | H2O: soluble1 M at 20 °C, clear, colorless |
| Impurities tested | ≤0.0005% Phosphorus (P)≤0.1% Insoluble matter |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
| Cation traces | Al: ≤0.0005%Ca: ≤0.0005%Cu: ≤0.0005%Fe: ≤0.0005%K: ≤0.005%Mg: ≤0.0005%NH4+: ≤0.05%Na: ≤0.005%Pb: ≤0.001%Zn: ≤0.0005% |
| Anion traces | chloride (Cl-): ≤0.05%sulfate (SO42-): ≤0.05% |
| Ignition residue | ≤0.1% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Pka 25 °C | 7.6 |
|---|---|
| Market Segment | Diagnostic Assay Manufacturing |
| Absorption | A1M/260, H2O ≤0.1A1M/280, H2O ≤0.05 |
| Useful Ph Range | 7.0 - 8.2 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is TAPSO used for?
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TAPSO is primarily used as a biological buffer in biochemical research and diagnostic assay manufacturing, maintaining stable pH conditions for experiments and biological samples.
What are the CAS number and chemical formula for TAPSO?
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The CAS number for TAPSO is 68399-81-5, and its chemical formula is C7H17NO7S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies TAPSO with an assay of ≥99% (titration). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should TAPSO be handled safely?
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TAPSO is classified as a warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure good ventilation and avoid breathing dust.
Is TAPSO a controlled substance?
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The provided data does not indicate that TAPSO is a controlled substance.
How is TAPSO packed and exported by TSS?
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Tech Serve Solutions packs and exports TAPSO according to industry standards for fine chemicals, ensuring product integrity during transit. Please contact us for specific export details.
How can I request a sample or quote for TAPSO?
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To request a sample or a quote for TAPSO, please contact our sales team through our website or by phone, providing your specific requirements.
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